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Explain the radiation cataract and steroid induced cataract of the eye.
Radiation Cataract
Exposure to radiation causes discoid posterior sub-capsular opacities. Mechanism of formation of cataract includes decrease in, GSH, decrease in enzyme levels, decrease in K, increase in Na, S-S bond and decrease in protein concentration.
Steroid Induced Cataract
Posterior sub-capsular cataract is the type of cataract associated with use of steroid. Mechanism of cataract formation is leukocyte inhibition, increased proteolysis, decrease in glycosaminoglycans and MYOC gene.
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