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Explain the radiation cataract and steroid induced cataract of the eye.
Radiation Cataract
Exposure to radiation causes discoid posterior sub-capsular opacities. Mechanism of formation of cataract includes decrease in, GSH, decrease in enzyme levels, decrease in K, increase in Na, S-S bond and decrease in protein concentration.
Steroid Induced Cataract
Posterior sub-capsular cataract is the type of cataract associated with use of steroid. Mechanism of cataract formation is leukocyte inhibition, increased proteolysis, decrease in glycosaminoglycans and MYOC gene.
Why do the sons of a haemophiliac father never vary from this trait? Why is the cleavage in mammals referred as simple homoplastic?
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