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Explain Adverse effects of Indinavir
In addition to adverse effects similar to those of other protease inhibitors, indinavir causes elevation of indirect bilirubin, indinavir-containing kidney stones and renal insufficiency, dermato- logic changes including alopecia, dry skin and mucous membranes, and paronychia and ingrown toenails. Patients should drink at least 1.5-2 liters of water daily to minimize renal adverse effects. Gallstones have also been reported.
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Topical Route The medication in topical route is administered through ear, nose and eye. Drops are instilled into the nose, ear and eyes of the child in much the same way
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