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What is Cyanosis ?
Cyanosis: Cyanosis may be peripheral or central. Peripheral cyanosis almost exclusively involves lips and extremities. Normal neonates may have bluish extremities that respond to warming or moving the extremities. Saturations of 90 per cent or lower while breathing room air beyond the first 20 minutes are considered abnormal. Similarly, some infants may have peripheral cyanosis following exposure to cold. Central cyanosis involving the mucous membranes and trunk along with the lips and extremities, strongly suggests the likelihood of CHD. Unfortunately, however, cyanosis often remains unnoticed. This is particularly true in the Indian context, where it is difficult to detect cyailosis is presence of a dark skin complexion. Further, cyanosis is often masked by anaemia. When central cyanosis is suspected, its presence should be confirmed and severity quantified by measuring oxygen saturation using a skin oxymeter probe. Unfortunately, however, the availability of this instrument is limited to a few selected institutions.
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Pulmonary Autograft and Ross Procedure : Sir Donald Ross in 1967 introduced the concept of using patient's own pulmonary valve (autograft) for aortic valve replacement and a pul
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Provide supporting evidence to explain how conversion of a normal somatic cell into a malignant one requires multiple mutations.
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Proteases of animals From the table you can see that these exopeptidases and endopeptidases attack specific peptide bonds depending on the chemical group near them. The inacti
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