Regulation of cholesterol biosynthesis, Biology

Assignment Help:

Cholesterol can be gained either from the diet or it can be synthesized de novo, mainly in the liver. Cholesterol is transported round the body in lipoprotein particles. The rate of synthesis of cholesterol is dependent on the cellular level of cholesterol. The High levels of cholesterol and its metabolites control cholesterol biosynthesis by:

-  Opinion-inhibiting the activity of HMG CoA reductase an enzyme that catalyzes the committed step in cholesterol biosynthesis;

-  Decreasing the amount of HMG CoA reductase by reducing the synthesis and translation of its mRNA;

-  Decreasing the amount of HMG CoA reductase by raising its rate of degradation.

 

 


Related Discussions:- Regulation of cholesterol biosynthesis

The non-oxidative phase generates ribose precursors, The non-oxidative ph...

The non-oxidative phase  generates  ribose precursors The non-oxidative phase of  the pathway,  including the following reactions, converts pentose-5-phosphate to other sugars.

Why do roots of many swamp plants have a special morphology, Why do roots o...

Why do roots of many swamp plants have a special morphology? Swamp and marsh plants usually present supporting roots that ramify from portions of the stem above the ground help

Phylum annelida, PHYLUM ANNELIDA Definition  and Introduction Bila...

PHYLUM ANNELIDA Definition  and Introduction Bilateral and  protosomial  eucoelomate  eumetazoans  whose  long   narrow and  wormlike body  is division  into  ring like  t

Chlorophyll and haemoglobin, dialouge on cartoon between chlorophyll and ha...

dialouge on cartoon between chlorophyll and haemoglobin

Disbeliefs about insulin injection, Some people have disbeliefs regarding i...

Some people have disbeliefs regarding insulin injection. You have to find out if there are any disbeliefs and try to explain the importance of insulin injection. Do not force the p

Which are the living beings that carry out photosynthesis, Which are the li...

Which are the living beings that carry out photosynthesis? Which is the cell organelle responsible for the absorption of light for the photosynthesis process in plants and algae?

Explain expansion in plasma volume during pregnancy, Normal 0 f...

Normal 0 false false false EN-IN X-NONE X-NONE

What is the action mechanism of the antibiotic penicillin, What is the acti...

What is the action mechanism of the antibiotic penicillin? Penicillin, discovered by the Scottish doctor Alexander Fleming in 1928, is a drug that inhibits enzymes essential fo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd