Pathophysiology of mitral stenosis, Biology

Assignment Help:

Q. Pathophysiology of mitral stenosis?

Normally there is no pressure gradient between left atrium and the left ventricle during diastole. However, as the valve orifice size decreases pressure gradient develops across mitral valve in diastole and the mean left atrial pressure increases. Increase in left atrial pressure would cause increase in the pulmonary artery wedge pressure. Increase in pulmonary artery wedge pressure would cause interstitial congestion by way of Starling's forces and this presents as symptoms of dyspnoea. Further rise in pulmonary artery wedge pressure causes pulmonary edema and pulmonary arterial hypertension. In some patients there will be disproportionate rise in pulmonary artery pressure due to vasoreactivity of pulmonary arteries. As the pulmonary artery systolic pressure increases further the right ventricle fails and features of right heart failure would ensue.


Related Discussions:- Pathophysiology of mitral stenosis

What is subphylum vertebrata explain, What is Subphylum Vertebrata explain?...

What is Subphylum Vertebrata explain? This large group of animals takes its name from its distinguishing feature: the vertebral column, or the backbone. The backbone made of se

Flowering and endogenous rhythms, Flowering and Endogenous Rhythms Th...

Flowering and Endogenous Rhythms The last four decades of studies in animals and plant physiology have clearly established the existence of a biological clock mechanism to me

Cloning of arg3 gene, 1)  You want to clone the arg3 gene, which encodes an...

1)  You want to clone the arg3 gene, which encodes an enzyme in the arginine biosynthetic pathway in Neurospora crassa.  You have available the E. coli plasmid vector shown in part

Explain the de bakey type i dissection, Explain the De Bakey Type I Dissect...

Explain the De Bakey Type I Dissection? De Bakey Type I Dissection :  Initial steps of the operation are same as previously described. Provision for deep hypothermic ci

Self- vs. cross-pollination, Self- vs. Cross-Pollination A major adva...

Self- vs. Cross-Pollination A major advantage of self-pollination is its certainty. Continued self-pollination over many generations, however, results in weaker progeny. This

Define the importance of iodine in human, Define the importance of Iodine i...

Define the importance of Iodine in human? Iodine derives the nutritional importance as a constituent of thyroid hormones, 3,5,3',5' tetraiodo-thyronine (thyroxine or T 4 ) and

Surveys - accidents in industries, Surveys - Accidents in Industries T...

Surveys - Accidents in Industries The surveys done in industries have pointed out that leading cause of accidents is the overexertion or workers working beyond their physical

Determine the symptoms of bacillus cereus, Determine the Symptoms of bacill...

Determine the Symptoms of bacillus cereus Extremely large numbers (10 8 per gram) of viable cells of B. cereus must be ingested to develop signs and symptoms of the syndrome.

Pleuritis, P l e u r iti s It is the acute or chronic inflammatio...

P l e u r iti s It is the acute or chronic inflammation of the pleural membranes. It is characterized by pain during respiration, pleural effusion, and shallow rapid resp

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd