Coenzyme A

Coenzyme A  is  derived  from  the  vitamin pantothenic  acid. This  is abbreviated  as CoA.  This  can  be  divided into  two  components, adenosine  3,5-diphosphate  and pantotheine, which  is  formed  by  the  combination  of  pantothenic acid and mercaptoethylamine. Refer Figure  to understand its structures well. It gives rise to  acyl-CoA  derivatives  that are  mainly formed  in  ATP  dependent synthetase reactions. These are highly  reactive and participate  in various types of reactions. For example, oxaloacetate  is  converted  to  citrate  in  presence  of  citrate synthetase  by accepting acyl group of acyl-CoA. During carbohydrate metabolism,  the pyruvate is converted by  the  pyruvate dehydrogenase complex  to  acetyl-CoA  by  the  active participation  of  coenzyme  A.