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Coenzyme A
Coenzyme A is derived from the vitamin pantothenic acid. This is abbreviated as CoA. This can be divided into two components, adenosine 3,5-diphosphate and pantotheine, which is formed by the combination of pantothenic acid and mercaptoethylamine. Refer Figure to understand its structures well. It gives rise to acyl-CoA derivatives that are mainly formed in ATP dependent synthetase reactions. These are highly reactive and participate in various types of reactions. For example, oxaloacetate is converted to citrate in presence of citrate synthetase by accepting acyl group of acyl-CoA. During carbohydrate metabolism, the pyruvate is converted by the pyruvate dehydrogenase complex to acetyl-CoA by the active participation of coenzyme A.
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