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1. Acetylation of key proteins is known to correlate with the gene expression in eukaryotes. What class of chromatin proteins is modified? What is the chemical nature of the acetylation that accounts for the alternation in a physical/structural sense? What features/interactions of DNA are altered? How could one detect segments of DNA in genes that were altered due to this phenomenon? What is the link between the modification and DNA sequence specificity? Be as specific as possible.
2. Compare and contrast gene expression in eukaryotes vs. prokaryotes from the standpoint of promoter sequences, complexes and RNA polymerase(s). What features are present in each that are distinct? What proteins, other than RNA polymerases are involved? What is known about the mechanism and ordering of gene expression in eukaryotes that makes it distinct from prokaryotic systems? Be specific, complete and structurally oriented in your answer as possible, given the level at which relevant topics are discussed in the text!
3. Gene inactivation correlates with methylation of DNA. What are the chemical/structural features of this process? How do pleuripotent cells differ from tumor cells in terms of the degree of methylation? Can you rationalize these differences in terms of known biochemical processes thought to be involved in the normal elimination of cells for the benefit of the organism?
copper reacts with oxygen to form two oxides es x and y on analysis 1.535 g of x yielded 1.365 g of copper and 1.450 g of y yielded 1.160 g of copper(1) determine the chemical for
what do you mean by the terms chromogen,auxochrome,bathochrome and hyposochrome?what role do they play in relation to colour and constitution?
A transition metal X has a configuration [Ar] 3d 4 in its +3 oxidation state. Its atomic number is: (1) 25 (2) 26 (3) 22 (4) 19 Ans: 25
Distillation under reduced pressure: Distillation under reduced pressure is widely used for the purification of liquids which have very high boiling points at atmospheric pres
how many blocks of elements are there /define p block elements
name and chemical formula of blue vitriol
The ratio of the concentration of the products raised to its stoichiometric coefficient to the concentration of the reactants raised to its stoichiometric coeff. Mostly, higher th
Molten sodium chloride conducts electricity due to the presence of: (1) Free electrons (2) Free ions (3) Free molecules (4) Atoms of sodium and chlorine Ans: Free
hittorf rule
Safety in Preparation of Preparation of trimethyl: 1 Use a round-bottomed flask equipped with a Claisen head (lagged with glass-wool), Quickfit thermometer (very expensive!)
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