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Describe the Clinical Evaluation MVP Murmur in details?
Characteristic: Mid systolic click followed by a late systolic murmur which usually extends to A2. The click may be absent and is not always followed by the late systolic murmur. Occasionally, murmur is high pitched and has been described as musical honk or whoop. In most patients with MVP, MR is trivial. Any maneuver that decreases the LV volume such as prompt standing, straining phase of Valsalva maneuver, amyl nitrite inhalation causes the valvular prolapse to occur earlier in systolic and therefore, the click and murmur move closer to S1.
The type of gene interaction in which effects of one gene override or mask the effects of other entirely different genes is known as: a) Mutation b) Linkage c) Pleitropy
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