Explain musculoskeletal pathophysiologic processes

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Question

Patient is a 44 year old male presenting with swollen, painful, red left knee for 2 days. Reports he is unable to bear weight on that leg. He is now also having toe pain. Symptoms started after the weekend when he attended a BBQ where he had 4 beers with his meal. He denies fever, rash or injury. BMI is 32. History of HTN, takes Hydrochlorothiazide, and works as a floor installer.

Aspiration of synovial fluid:

Monosodium urate (MSU) crystals positive

Lab results

Lab Result Reference Range

Uric Acid 8 3.5 and 7.2 mg/dL

ESR 65 0-15 mm/hr

CRP 10.5 <0.3 mg/dL

- Identify key symptoms presented that will help to determine the diagnosis.

- Explain the musculoskeletal pathophysiologic processes of why the patient presents these symptoms.

- Explain how obesity plays a role in the progression of osteoarthritis/gout in the knee joints.

- Explain risk factors that may contribute to the development of the disease.

Reference no: EM133875426

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