Explain wound healing and formation of woven bone, Biology

Wound healing and formation of woven bone

Stage 1: Wound healing and formation of woven bone (callus) (2 to 6 weeks)

The ability of the body to respond to the "trauma" induced by implantation will influence the kind of tissue response (and hence the degree of integration). Therefore proper surgical handling of the tissues with minimal generation of heat (<47º C for 1 minute or less) during preparation of the surgical site will provide the most predictable healing response.

After the formation of initial clot around the surgical site, a minor inflammatory response occurs which includes the proliferation and differentiation of numerous phagocytes and undifferentiated mesenchymal cells from the adjacent periosteum. The ability of the tissues to differentiate will depend on the presence of an intact vascular bed that provides adequate oxygenation for bone differentiation.

With the initial placement of the implant, a thin (about 0.5mm) layer of bone in the prepared site will become necrotic from the process of forming the implant site. This bone is replaced by the body as integration proceeds. Initially, an in growth of vascular loops will occur at the rate of 0.5mm per day followed by initial woven bone formation in the first two weeks after initial surgical implant placement. Due to the inert nature of the oxide surface, newly differentiating osteoblastic cells derived from the adjacent periosteum synthesizes woven bone matrix that provides initial bone contact with the oxide surface.


Posted Date: 7/24/2013 6:26:41 AM | Location : United States

Related Discussions:- Explain wound healing and formation of woven bone, Assignment Help, Ask Question on Explain wound healing and formation of woven bone, Get Answer, Expert's Help, Explain wound healing and formation of woven bone Discussions

Write discussion on Explain wound healing and formation of woven bone
Your posts are moderated
Related Questions
Define Absorption, Storage and Elimination of Pyridoxine? Pyridoxine, pyridoxal and pyridoxamine (along with their phosphorylated forms) occur in plant and animal foods. The ph

Q. Described Microbiology of Air? Ans. You would realize that air, by nature, does not contain a natural flora of microorganisms. All that comes into air is by accident and i

Elaborate Immune Response system and their categories? The immune response is a group of defenses that the body has developed to combat disease-producing agents, or pathogens.

Explain the Etiology and Clinical Features of Parkinson's disease? The cause of Parkinson's is unknown. Genetic predisposition (in most cases the reason for the death of these

How was it proved in the case of Amoeba that the key to the life of a cell is Nucleus?

Wind pollinated flowers are: 1. Small, brightly coloured, producing large number of pollen grains 2. Small, producing large number of dry pollen grains 3. Large producing

Complications of Exchange Transfusion i) Infection of umbilical vessels and systemic injection related to blood transfusion like malaria, CMV, AIDS and hepatitis B. ii) O

Which of the following statements about how B and T cells recognize antigen are true? a. B cells only recognize antigen presented by class I or class II MHC molecules. b. Both cell

Sludge treatment and disposal: most of the suspended solids and some of the dissolved organic solids, in a converted form, are separated from the main flow of the, in the form of

Q. What are the main biological functions of water? Ans. Water is the basic solvent for chemical reactions of living beings; it is the main means of substance transportati