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Which of the following is true for a G-protein?
A. After the ATP-ase of the alpha subunit of a G protein converts the ATP bound to the alpha subunit to ADP and inorganic phosphate (Pi ), the alpha subunit of the G-protein recombines with the beta and gamma subunits of the G-protein.
B. When an antagonist binds to the binding site of a G-protein-coupled receptor (GPCR), this leads to GTP displacing a GDP bound to the alpha subunit of the G-protein.
C. When GDP binds to an alpha subunit of the G-protein, this leads to the alpha subunit of the G-protein dissociating from the beta and gamma subunits of the G-protein.
As heart failure sets in, there is activation of RAS (Fig 2.1). Adrenergic stimulation of beta-1 receptors in juxtaglomerular apparatus of the kidneys results in release of renin.
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