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Q. In sickle cell anemia, a hereditary disease, there is replacement of one amino acid by another in one of the four polypeptide chains of hemoglobin. In this case are all of the structural levels of the protein modified?
In sickle cell disease there is a modification in the primary protein structure of one of the polypeptide chains that form haemoglobin, the amino acid glutamic acid is substituted by the amino acid valine in the β chain. The spatial conformation of the molecule in addition is also modified and affected by this primary "mistake" and the modification also creates a different (sickle) shape to the red blood cells.
Sickled, Modified, red blood cells sometimes aggregate and obstruct the peripheral circulation causing tissue hypoxia and the pain crisis typical of sickle cell anemia.
State the term - Early therapeutic Intervention Since outcome may be ameliorated by well timed and appropriate treatment, the prevailing belief is that dysfunction should be id
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Eric Davidson isolated and compared the sequences of mRNA transcripts and genomic DNA from the sea urchin. Which of the following is a true statement regarding his findings? A.
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State about polyploid cells During development cells of certain tissues like the salivary gland and liver produce extraordinary amounts of selected proteins. This is often achi
List three human activities which could cause the loss of a species. Human activities which threaten species with extinction are: (i) hunting of individual species, (ii) over-
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bone modeling may occur?
The entire mechanism of protein synthesis in eukaryotes is generally the same as in prokaryotes, with three phases explained as termination, elongation and initiation. Furthermore,
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