Osteogenesis: Production of Bone on Soft Tissue

Now that we know the players in bone adaptation, we will look at the ways in which bone may be created and modified. There are three major ways bone tissue may be altered: 1) osteogenesis, 2) modeling and 3) remodeling. The alterations differ basically in the tissue on which bone is placed and the way in which osteoblasts and osteoclasts work together. Osteogenesis is the production of bone on soft tissues, either soft fibrous tissue or cartilage. It is the way in which bones are formed during embryonic development and how bone is initially formed at the site of injury, for example in fracture healing.