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Most proteins made by ribosomes on the RER (rough endoplasmic reticulum) are glycoproteins, which is they hold short chains of carbohydrates (oligosaccharides) covalently related to them during passage by the Golgi and RER complex. Two major types of oligosaccharide linkage exist:
? O-linked oligosaccharides are commonly attached to the protein through O-glycosidic bonds to OH groups of Thr or Ser side chains. The residues which are changed are frequently in a region of the polypeptide chain which is rich in Thr and Ser residues. In plant glycoproteins, the OH sets of hydroxyproline (Hyp) residues can be glycosylated, by the hydroxylysine (Hyl) reduce in the mammalian protein collagen can be O-glycosylated.
? N-linked oligosaccharides are related to the protein via N-glycosidic will bonds to the NH2 where the Asn occurs in the sequence Asn-X-Ser (or Thr) where X is many amino acids except Pro. If the Asn is N-glycosylated the Thr or Ser residue in this motif is not O-glycosylated.
State Diploblastic in brief. Organisms formed from only two primitive cell layers- ectoderm and endoderm. Though there may be some type of a matrix between two cell layers, gen
While discussing the Darwinian premise of natural selection we observed that the term selection is synonymous with non-random reproduction, and that the success of the survivors is
Define Vitamins, Minerals and Phytochemicals requirement for cancer patients? Several vitamins particularly those of the B-group are essential to promote adequate metabolism of
Careful palpation of the upper and lower limb pulses would make one suspect coarctation as the cause of hypertension. The lower limb pulses are weak and delayed. Confirmation ca
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A charged particle A exerts a force of 2.39uN to the right on charged particle B when the particles are 12.3 mm apart. Particle B moves straight away from A to make the distance be
Define Microscopical Examination of Starch Granules? Take a slide and make a thin film of a suspension of starch granules from different sources and examine under a microscope.
Q. What are some strategies of the anti-retroviral drugs used in the AIDS treatment? The Anti-retroviral drugs used in AIDS treatment try to approach any of the several steps o
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