Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Signify the term metacoel, Signify the term Metacoel. The last of three...

Signify the term Metacoel. The last of three coelomic spaces found in tripartate body plan characteristic of deuterostome lineage of animals. Other coelomic compartments are th

Tautomeric shifts, The original DNA sequence when ,transcribed and translat...

The original DNA sequence when ,transcribed and translated would yield five successive valine residues. But the altered sequence would correspondingly read one aspartate and four s

Which are the heart chambers, Q. Which are the heart chambers respectively ...

Q. Which are the heart chambers respectively where the entrance and the exit of blood occur? The heart chambers through which blood enters the heart are the atria there are the

Cells, what are golgi apparatus

what are golgi apparatus

Describe genetic equilibrium is maintained in population, a) How does the H...

a) How does the Hardy- Weinberg's expression (p²+2pq+q² =1) Describe that genetic equilibrium is maintained in a population? (b)  List any two factors that can disturb the ge

Plasma membrane proteins, Integral plasma membrane proteins are also synthe...

Integral plasma membrane proteins are also synthesized by ribosomes on the RER, but become inserted in the rough endoplasmic reticulum membrane rather than transported into the lum

Colibacillosis of poultry, Colibacillosis of poultry Colibacillosis is...

Colibacillosis of poultry Colibacillosis is an important disease among poultry, especially among broiler chicks aged 6-9 weeks and less frequently of young chicks during first

Orthopedics, 1. List alternative therapies for musculoskeletal problems. ...

1. List alternative therapies for musculoskeletal problems. 2. What is a xyrospasm? What is the Greek derivative of the word? 3. Name and describe the three types of varus con

What are the kinds of plant geotropisms, What are the kinds of plant geotro...

What are the kinds of plant geotropisms? Why do the root and the stem present opposite geotropisms? The kinds of geotropisms are the positive geotropism, that in which the plan

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd