Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Strategie of the anti-retroviral drug used in aids treatment, Q. What are s...

Q. What are some strategies of the anti-retroviral drugs used in the AIDS treatment? The Anti-retroviral drugs used in AIDS treatment try to approach any of the several steps o

Symptoms of malabsorption syndrome, Q. Symptoms of malabsorption syndrome? ...

Q. Symptoms of malabsorption syndrome? The most common symptoms are weakness, lassitude and marked weight loss. Steatorrhoea (excess fat in stools), anaemia and chronic ill h

Explain about the protein-energy ratio, Explain about the Protein-Energy Ra...

Explain about the Protein-Energy Ratio (NDP Cal%)? Platt and his colleagues (1961) are largely responsible for the introduction of the ratio of protein energy to total energy (

Run off-water cycle, Run off Some of the rainfall is soaked into the so...

Run off Some of the rainfall is soaked into the soil and excess water flows over the land surface along the natural slope of the area. Run off is the main source of water for l

Describe amoebae - paramecia and trichomonas, Q How do amoebae, paramecia a...

Q How do amoebae, paramecia and trichomonas respectively move? Amoebae move by amoeboid movements small invaginations and projections of their plasma membrane (pseudopods) that

Explain about the deranged lipid profile, Explain about the Deranged lipid ...

Explain about the Deranged lipid profile? Lipids, as you are already aware, are important dietary constituents that include fats, steroids, phospholipids and glycolipids. A num

The protective structures of the central nervous system, What are the prote...

What are the protective structures of the central nervous system present in vertebrates? In vertebrates the brain and the spinal cord are protected by membranes, the meninges,

Define the functional properties of proteins, Define the Functional Propert...

Define the Functional Properties of Proteins? a) Hydration properties (dependent on protein-water interactions), which include properties like swelling, adhesion, dispersibilit

Define consistency and texture - dysphilgia, Define Consistency and Texture...

Define Consistency and Texture - Dysphilgia? Aspiration of liquids, including water, into the lungs can result in complications. To avoid this problem and yet fulfilling the fl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd