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Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.
Q. What is the kind of circulatory system present in arthropods? Do these animals have respiratory pigments and heart? In arthropods the respiratory system is open (lacunar). B
Water Absorption Water status of a plant is determined by two major factors: i) water absorption and ii) water loss. We deal with water absorption in this section and water lo
Q. How be able to the excretory system of annelids be described? In each segment (metamere) of the being a pair of complete excretory structures known as metanephridium exists.
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