Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Explain three parts of homogenate, Differential centrifugation divides cell...

Differential centrifugation divides cellular components based on the differences in their size and / or density. A tissue sample was homogenized and three parts (aliquots) of this

Define the enzyme deficiency or defects, Define the Enzyme deficiency or de...

Define the Enzyme deficiency or defects? A food sensitivity or intolerance can occur when the body has difficulty in digesting a particular food and therefore reacts against it

Evolution and growth of sports nutrition as a discipline, Define Evolution ...

Define Evolution and Growth of Sports Nutrition as a Discipline? An academic discipline is basically a formal body of knowledge discovered, developed, and disseminated through

What is diatoms, What is Diatoms? Bacillariophyta are commonly known as ...

What is Diatoms? Bacillariophyta are commonly known as diatoms because of their unique structure. These unicellular photosynthetic organisms are composed of two overlapping glas

List some differences between a bacteria and a virus, Question 1: (a) L...

Question 1: (a) List some differences between a bacteria and a virus? (b) Define‘Swine Flu'. List the main types of ‘Swine Flu' viruses? (c) Describe the preventive measures

Explain ophthalmic, Ophthalmic Data are limited on the effectiveness of...

Ophthalmic Data are limited on the effectiveness of antimicrobial prophylaxis for ophthalmic surgery, but postoperative endophthalmitis can be devastating. Most ophthalmologist

What are the plant cell vacuoles, Q. What are the plant cell vacuoles? And ...

Q. What are the plant cell vacuoles? And what are their functions? And what is the covering membrane of the vacuoles called? Plant cell vacuoles are cell structures delimited b

Wildlife - ecology, Wildlife - Ecology The term wildlife probably orig...

Wildlife - Ecology The term wildlife probably originated in 1913 in a book, Our Vanishing Wildlife by William Hornaday, Director of the New York Zoological Park. The main focu

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd