Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Determine the intracellular concentration of trva, Determine the intracellu...

Determine the intracellular concentration of TRVA Consider Neuron B in the frog central nervous system whose plasma membrane has a previously unknown channel that is selectly c

Salt glands in birds and reptiles, Salt Glands in Birds and Reptiles M...

Salt Glands in Birds and Reptiles Marine reptiles for example, iguanas, estuarine sea turtles, crocodiles, sea snakes and marine birds like the marine teleosts do not produce

Medication therapy and nursing consideration, Mr. Smith is a 72 year male d...

Mr. Smith is a 72 year male diagnosed with hypertension.  Along with hypertension, Mr. Smith has been diagnosed with right-sided heart failure.  The following are his list of medic

Cellular type - endosperm, Cellular Type - Endosperm In this type, as...

Cellular Type - Endosperm In this type, as the name indicates, the division of the primary endosperm nucleus is immediately followed by the laying down of a wall, which is us

Mitral valve replacement, Mitral Valve Replacement :  When mitral...

Mitral Valve Replacement :  When mitral valve replacement for a calcified, stenotic valve is done, usually it is a classical procedure removing leaflets, their chordae an

Pbpk modeling during human drug development, Early human studies are normal...

Early human studies are normally conducted in healthy subjects to assess acute safety and, if applicable, to monitor biochemical and pharmacological responses. These studies also p

Name the enzyme present in saliva, Name the enzyme present in saliva and sa...

Name the enzyme present in saliva and say what type of food it acts on.   The enzyme in saliva is salivary amylase and it acts on starch.

Erythrocytes or red blood cells, Erythrocytes or red blood cells: Th...

Erythrocytes or red blood cells: These are otherwise called Red Blood cells or corpuscles. These are the most numerous cells in the blood.There are about 4.5 to 5.5x 10 9

Functions of endoplasmic reticulum, FUNCTIONS OF E.R. (1 )      Mecha...

FUNCTIONS OF E.R. (1 )      Mechanical support - E.R. participates in formation of cytoskeleton with microfilaments, microtubules and intermediate filaments. (2 )

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd