Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

What do you mean by polyphagia, Q. What do you mean by Polyphagia? Incr...

Q. What do you mean by Polyphagia? Increased Hunger (Polyphagia): As patient is losing more sugar in the urine, he feels hungry very soon and tends to take more food. It is cal

Colluvial-transported soil, Colluvial These are the soils formed from t...

Colluvial These are the soils formed from the material transported by the pull of gravity. Fragments from cliffs or steep rocky slopes become dislodged from time to time and ma

Define the anatomical considerations, Define the Anatomical Considerations ...

Define the Anatomical Considerations 1. Neurovascular bundle associated with greater palatine foramen, e.g. palatal root of the upper 1 st molar: Don't do incision at this area

Define placental transfer of nutrients, Define Placental Transfer of Nutrie...

Define Placental Transfer of Nutrients? The placenta is n transitory structure developing during pregnancy and lies implanted on the uterine wall. It is connected with the foet

What is ridge morphology, What is Ridge morphology The implant-supporte...

What is Ridge morphology The implant-supported prosthesis is affected by the ridge morphology especially implant-supported overdentures which gain dual support from implants an

How are ecological interactions classified, Q. How are ecological interacti...

Q. How are ecological interactions classified? Ecological interactions are classified as interspecific or intraspecific interactions and as harmonious or inharmonious interacti

Excretory organs, classification of excretory organs in helminthes, nermato...

classification of excretory organs in helminthes, nermatodes, annelids, molluscs, arthropods and echinodems

Types of ecosystem, Ecosystems are so varied in form and structure that wha...

Ecosystems are so varied in form and structure that whatever has a distinct community of its own, can be called an ecosystem eg. A crop field, grass land, barks etc. all the ecosys

Formation of an h+ gradient, All of the electron carrier in the electron tr...

All of the electron carrier in the electron transport chain interact according to their redox potentials.  Every time whereas an electron transfers occurs, the accepting carrier ha

Corelation of st depressoin with coronary angiography, Q. Corelation of ST ...

Q. Corelation of ST Depressoin with Coronary Angiography? Various investigators considered 1 mm of horizontal or downsloping ST depression to denote a positive test and used fr

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd