Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Understanding life, UNDERS T ANDIN G LIF E - Presence of proto...

UNDERS T ANDIN G LIF E - Presence of protoplasm is the important feature of life which acts the site of metabolism. Maintenance of life by protoplasm requires conti

A field trip to observe flowers, A field trip to observe flowers:- Plan...

A field trip to observe flowers:- Plan a field trip to view flowers in bloom. If no interesting wildflowers can be found growing near the school, the trip can be planned to a p

What capacity of hemoglobin include, Manifestations of anemia that are dire...

Manifestations of anemia that are directly due to the diminished oxygen-carrying capacity of hemoglobin include: Answer A. pale skin. B. bleeding. C. bone pain. D. fatigue.

Use of metals and alloys in alloplastic implant materials, Metals and Alloy...

Metals and Alloys in alloplastic implant materials Most of the dental implant systems are made of metals or their alloys. Currently commercially pure titanium and its alloy Ti-

Which enzyme acts on pyruvate in mitochondria, Which enzyme acts on pyruvat...

Which enzyme acts on pyruvate in mitochondria and converts it to acetyl CoA?Name its components and cofactors associated with it. Pyruvate dehydrogenase complex acts on pyruvate

Can you explain about cardiomyopathies, Q. Can you explain about Cardiomyop...

Q. Can you explain about Cardiomyopathies? Cardiomyopathy is a primary disorder of heart muscle that may cause cardiac dysfunction and is not related to any obvious disease pr

Statistical investigation, Meaning of Statistical Investigation: An inv...

Meaning of Statistical Investigation: An investigation means a systematic search for the knowledge or the truth. In statistical investigation the search for the knowledge is do

Gene, Gene  is the fundamental physical and functional unit of the heredity...

Gene  is the fundamental physical and functional unit of the heredity (generally DNA, Some of the organisms have RNA a gene). A gene is an ordered series of nucleotides located in

Difference between fat-soluble and water-soluble vitamins, Q. What is the d...

Q. What is the difference between fat-soluble and water-soluble vitamins? Why can fat-soluble vitamins cause harm when ingested in excess? Water-soluble vitamins are those vita

Cell, The scientist who described cells as “many little boxes” was

The scientist who described cells as “many little boxes” was

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd