Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Explain the toxicity of nicotinic acid, Explain the Toxicity of nicotinic a...

Explain the Toxicity of nicotinic acid? Although therapeutically useful in lowering serum cholesterol, administration of chronic high oral doses of nicotinic acid can lead to h

Radiography, RADIOGRAPHY You  have read  in GNM courses about radiographi...

RADIOGRAPHY You  have read  in GNM courses about radiographical examination. In this text the discussion will be on the following radiographical tests.   Chest Roentgenogram

Pattern of cleavage, define the pattern of cleavage i all aspects

define the pattern of cleavage i all aspects

Explain the function of myosin and albumin, What are respectively some rema...

What are respectively some remarkable functions of myosin, CD4, albumin, keratin, immunoglobulin, reverse transcriptase, hemoglobin and insulin? Myosin is a protein that when a

dna repair, is mismatch repair something different from proofreading

is mismatch repair something different from proofreading?

Describe induced ventricular arrhythmias, Q. Describe Induced Ventricular A...

Q. Describe Induced Ventricular Arrhythmias? The prognostic significance of ventricular ectopy provoked by stress testing after an MI is controversial. Complex ventricular arrh

How many carbon dioxide molecules liberated in krebs cycle, Q. How many car...

Q. How many carbon dioxide (CO 2 ) molecules are liberated after each cycle of the Krebs cycle? For a single glucose how many carbon dioxide molecules were already liberated by the

Determine the term memory - psychological tests, Determine the term Memory ...

Determine the term Memory - Psychological tests The acquisition, reaction, and retrieval of new information is a domain of much importance in infants and young children at risk

Which animals maintain constant body temperature?, Which of the below terms...

Which of the below terms is used to describe animals which maintain a constant body temperature by producing heat by metabolic oxidations (muscle contractions) and losing excess he

What is mucic acid test and its principle, What is Mucic Acid Test and its ...

What is Mucic Acid Test and its principle? This is a specific test for galactose and is given by galactose as well as lactose, which is made up of galactose and glucose. Pr

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd