Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

what is the optimum temperature for catalyses, Explain What is the optimum...

Explain What is the optimum temperature for catalyses? Ans) For any chemical reaction, the reaction rate enhances with temperature, so the higher the temperature, the earlier t

Alfieri repair-technique of operation, Alfieri Repair: This is advised ...

Alfieri Repair: This is advised for ischaenlic mitral regurgitation. In the area of prolapse, the anterior and posterior leaflet edges are approximated with one or two mattress

Define about the nutritional deficiencies, Define about the nutritional def...

Define about the nutritional deficiencies? The nutritional deficiencies which have been identified in the group of elderly are of total calories, protein, vitamin A, vitamin C,

What is the function of glucose-6-phosphatase, What is the function of gluc...

What is the function of glucose-6-phosphatase? a) catalyze removal of one phosphate group from glucose b) catalyze removal of six phosphate groups from glucose c) catalyze the remo

Characteristics of female''s skeleton, CHARACTERISTICS OF FEMALE'S SKELETON...

CHARACTERISTICS OF FEMALE'S SKELETON - 1.      Skull is lighter. 2.      Shoulders are nanow. 3.      Sacrum is shorter but wider. 4.      Pelvis is wider. 5.

Micro-organisms, Micro-organisms: The micro-organisms mixed up i...

Micro-organisms: The micro-organisms mixed up in aerobic absorption and their activities are the same as those found in nature. The organic compounds are oxidised to H

Polysaccharide sugars, Polysaccharide - polymer composed of monosaccharide...

Polysaccharide - polymer composed of monosaccharide monomers Starch - Energy storage in plants à straight (amylose) and branched (amylopectin) chains of α-glucose Glycogen

Define fluid and electrolytes requirements in elderly, Define Fluid and Ele...

Define Fluid and Electrolytes requirements in elderly? Care lo be taken that adequate fluid be given to the elderly. If patient is unable to take the required daily needs, then

Wetlands and estuaries, Wetlands and estuaries are transitional biomes. Lan...

Wetlands and estuaries are transitional biomes. Land that remains flooded either part of the year or permanently with fresh or salt water is known as wetland. The internationally a

Intravenous drug abusers, The risk for IE among IV drug abusers, 2 to 5 per...

The risk for IE among IV drug abusers, 2 to 5 per cent per patient- year, is estimated to be several fold greater than that of patients with rheumatic heart disease or prosthetic v

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd