Explain about metabolic diseases, Biology

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Q. Explain about Metabolic diseases?

Metabolic diseases, as you already know, refer to those disorders in which the various reactions in the cells are effected (production of energy or utilization of energy) due to abnormal production of one or more hormones, cop. a deficiency of an enzyme. Most metabolic disorders are genetic, though a few are "acquired" as a result of diet, toxins, infections, etc. Metabolic disorders or inborn errors of metabolism are inherited traits that result in the absence or reduced activity of a specific enzyme or cofactor.In general, these genetic metabolic disorders are caused by genetic defects that result in missing OF improperly constructed enzymes necessary for some step in the metabolic process of the cell. Phenylketonuria, tyrosinernia, maple syrup urine disease, homocystinuria and galactosemia are some common metabolic diseases caused by genetic defects.

Gout is yet another metabolic disease caused due to a disturbance of uric acid metabolism occurring chiefly in males, characterized by painful inflammation of the joints, especially of the feet and hands, and arthritic attacks resulting from elevated levels of uric acid in the blood and the deposition of rate crystals around the joints. The condition can become chronic and result in deformity.


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