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Achondroplasia is an autosomal dominant disorder associated with a gene on chromosome 4. Sickle cell anemia is due to a gene on chromosome 11. A man and a woman with achondroplasia, who each had a normal parent, are carriers for sickle cell anemia.
a. Give the genotypes of these individuals; provide a legend for your symbols.
b. Construct a Punnett square to determine the possible types of offspring these two people could have together.
c. Summarize the Punnett square to list the genotypes and their ratio.
d. List the possible phenotypes and the expected proportions of these phenotypes.
e. What is the name for this type of cross?
f. If these genes had been on the same chromosome, would you expect the same results for potential offspring? Why or why not?
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