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Disorder of Platelets - Purpura
Purpuras are bleeding disorders characterised by petechiae and ecchymosis which may be due to deficiency in either, the number or quality of platelets or defect in the vascular endothelium.
Idiopathic thrombocytopenic purpura (ITP): Idiopathic thrombocytopenic purpura is the most common acquired thrombocytopenic disorder in children. It is characterised by a haemorrhagic condition involving the skin, mucous membrane and internal organs. Its greatest incidence is between three and seven years of age. Thrombocytopenia is the result of rapid platelet destruction because of presence of platelet antibodies.
Etiology
The cause of ITP is unknown. It is said to be an autoimmune response to disease related antigens. The acute form of (ITP) is believed to be related to sensitization by viral infection such as rubella, chicken pox or viral respiratory infection.
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