Define fluconazole, Biology

Assignment Help:

Define Fluconazole

It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclosporine, simvastatin  (Zocor) and lovastatin (Mevacor, and others). Fluconazole is a strong inhibitor of CYP2C9 and can therefore enhance serum concentrations of tacrolimus, phenytoin (Dilantin, and others), zidovudine (Retrovir), warfarin (Coumadin, and others) and other drugs metabolized by 2C9. Concomitant administration of rifampin (Rifadin, and others) can lower serum concentrations of fluconazole.

 


Related Discussions:- Define fluconazole

Tuberculosis, Tuberculosis Tuberculosis is caused by a Bacillus-myco...

Tuberculosis Tuberculosis is caused by a Bacillus-mycobacterium tuberculosis, a gram- positive and acid-fast organism. It is communicable disease. Mode of Transmissio

Types of ecosystem, Types of Ecosystem Basically ecosystems are of two ...

Types of Ecosystem Basically ecosystems are of two types : terrestrial and aquatic. If you travel from plains to the mountains in the Himalayas, you notice significant changes

Define biodiversity and ecosystem stability, Define Biodiversity and ecosys...

Define Biodiversity and ecosystem stability? Human's have transformed ecosystems all through the world, frequently replacing diverse natural ecosystems with ecosystems which ar

What are the general necessities for surgery, General necessities for surge...

General necessities for surgery The actual surgical technique of dental implant placement, it would be appropriate to recapitulate the basic principles of surgery. The two prin

Explain about the transcellular route - calcium, Explain about the Transcel...

Explain about the Transcellular Route - Calcium? Transcellular Route: It operates primarily in the duodenum and proximal jejunum. It is stimulated when Ca ingestion is lower re

Illustrate the tyndallisation, Q. Illustrate the tyndallisation? John T...

Q. Illustrate the tyndallisation? John Tyndall devised a process of sterilisation by steaming for a few minutes at 100 o C on 3-4 successive operations separated by 24 hour in

Medical records, Medical Records This includes: health history o...

Medical Records This includes: health history of patient/client  a report of the findings on examination  signs and symptoms  observation records  progress

Botany, Sir/Madam, I am a Banquet Farm Owner and face the problem with the ...

Sir/Madam, I am a Banquet Farm Owner and face the problem with the Grass that in November & December the grass does not grow well or disappear beacuse of heavy foot fall. Is their

Explain continuous full - thickness incision, Q. Explain Continuous full - ...

Q. Explain Continuous full - thickness incision? Continuous full - thickness incisions are indicated for a variety of situations outlined below. This type of incision may be us

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd