Define fluconazole, Biology

Assignment Help:

Define Fluconazole

It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclosporine, simvastatin  (Zocor) and lovastatin (Mevacor, and others). Fluconazole is a strong inhibitor of CYP2C9 and can therefore enhance serum concentrations of tacrolimus, phenytoin (Dilantin, and others), zidovudine (Retrovir), warfarin (Coumadin, and others) and other drugs metabolized by 2C9. Concomitant administration of rifampin (Rifadin, and others) can lower serum concentrations of fluconazole.

 


Related Discussions:- Define fluconazole

Why are we not inundated with bacterial infections, We are told that every ...

We are told that every surface we touch is teeming with bacterial cells, and bacteria are found in the pools we swim in, the water we wash with, and on the hands of friends. Why ar

Final atp count in both prokaryotes and eukaryotes, Degrade a monoglyceride...

Degrade a monoglyceride that has an 18-carbon fatty acid attached to it by Ester bonds. You will have to degrade the glycerol component followed by the fatty acid in presence of O2

Define estimation of nitrogen and protein content, Estimation of Nitrogen a...

Estimation of Nitrogen and Protein Content Using Micro Kjeldahl's Method? Standardization of H 2 SO 4 Prepare a solution of 0.1 N H 2 SO 4  by diluting 2.8 ml of the con

Explain in detail about gene therapy, Explain in detail about Gene therapy ...

Explain in detail about Gene therapy Gene therapy technology as a whole has yet to be proven and it's meeting a number of stumbling blocks, so may have little impact (low succe

Explain acyclovir, Explain Acyclovir Available in topical, oral, and in...

Explain Acyclovir Available in topical, oral, and intravenous (IV) formulations, acyclovir is used to treat herpes simplex virus (HSV) and varicella-zoster virus (VZV) infectio

Pollutants, These are solid, liquid or gaseous substance present in the atm...

These are solid, liquid or gaseous substance present in the atmosphere in such concentrations, as may be or tend to be injurious to human beings or other living creatures, plants a

Excretion in animals, Excretion in Animals Excretion is concerned alon...

Excretion in Animals Excretion is concerned along with the removal of metabolic wastes that arise as a result of oxidation of energy rich compounds and metabolism of proteins

Compute the osmolarity of a solution, Calculate the osmolarity of a solutio...

Calculate the osmolarity of a solution of 5% dextrose in water (dextrose = glucose, molec. Wt. = 180).

Explain the magnesium deficiency and toxicity, Explain the Magnesium Defici...

Explain the Magnesium Deficiency and Toxicity? Deficiency of magnesium is rare for two reasons: frstly, the mineral is widely distributed in the foods, secondly, kidney is able

What is gastritis, Q. What is Gastritis? Gastritis is an inflammatory l...

Q. What is Gastritis? Gastritis is an inflammatory lesion of the gastric mucosa, (the inner lining of the stomach). The problem is seen in two forms: a) Acute gastritis

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd