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Define Fluconazole
It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclosporine, simvastatin (Zocor) and lovastatin (Mevacor, and others). Fluconazole is a strong inhibitor of CYP2C9 and can therefore enhance serum concentrations of tacrolimus, phenytoin (Dilantin, and others), zidovudine (Retrovir), warfarin (Coumadin, and others) and other drugs metabolized by 2C9. Concomitant administration of rifampin (Rifadin, and others) can lower serum concentrations of fluconazole.
What is Barfoed's test and its principle? This test is a specific test for monosaccharides. Principle This test is also a copper reduction test but differs from Fehling
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URINARY BLADDER - Pear shaped sac like. Situated in pelvic region of abdominal cavity. Ventrally placed. Lined by transitional epithelum. Detrusor muscle i.e. to expell out
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