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Adverse Effects
The most common adverse effects of itraconazole are dose-related nausea and abdominal discomfort. Rash and serious hepatic toxicity can happen. The drug can cause hypokalemia, edema and hyper-tension. Congestive heart failure has been reported with itraconazole and the drug should not be used in patients with ventricular dysfunction.
Thrombocytopenia and leukopenia have also been reported. The intra-venous formulation have cyclodextrin, which can accumulate in azotemic patients; its use is not recommended in patients with creatinine clearance <30 mL/min.
Intravenous Route This route of administering drugs is becoming more popular in the paediatric practice. Purpose of this Route When rapid action is required.
Genetic Diversity of Population The biological diversity of animals, plants, and microorganisms is of fundamental importance to human survival. The term "gene resources" may b
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Prophylaxis Many experts recommend that sexually assaulted adults and adolescents be given treatment to prevent sexually transmitted infections, including therapy for gonorrhea
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