Anticoagulants, Biology

Assignment Help:

ANTICOAGULANTS

(a) Heparin (hepar = liver) . It is synthesized by mast cells of connective tissue and liver cells. It is a heteropolysaccharide. It increases the effectivity of antithrombin III (a - globulin) which inactivates the thrombin so prevents conversion of fibrinogen into fibrin.

(b) Hirudin. It is an anticoagulant present in the saliva of salivary glands of leech and is mixed with blood of host during its storage in its crop.

(c) Warfarin. It is an anticoagulant of plant origin, which when given to a patient, lowers the formation of prothrombin and factors VII, IX and X from liver cells by lowering the activity of Vitamin K.

(d) Sodium oxalate, sodium citrate and EDT A (Ethylene diamine tetra acetic acid) are used as anticoagulants in blood banks as these bind Ca++, so these are called chelating agents. .

(e) Chilling of blood also delays blood clotting as it lowers the activity of enzymes involved in blood clotting.

 

ROLE OF VITAMIN-K IN BLOOD CLOTTING -

Vitamin K, also called anti-haemorrhagic factor, is a fat soluble vitamin and is essential for the formation of prothrombin from the liver. Deficiency of vitamin K causes hypoprothrombinemia which interferes with blood clotting. Vitamin K is also synthesized by intestinal bacteria.


Related Discussions:- Anticoagulants

Endocine organ, #question.endocrine organ in crustaceans

#question.endocrine organ in crustaceans

What is starch , Starch exists in plants as insoluble starch granules in c...

Starch exists in plants as insoluble starch granules in chloroplasts.  Each starch granule   holds   a   combination   of   two   polysaccharide    forms, amylopectin and amylose.

What is the neuromuscular synapse, Q. What is the neuromuscular synapse? ...

Q. What is the neuromuscular synapse? Neuromuscular synapse is the structure through which the neural impulse passes from the axon of a motor neuron to the muscle cell. This st

Rare species - wildlife, Rare Species - Wildlife These are those speci...

Rare Species - Wildlife These are those species whose numbers are few or they live in such small areas or in such unusual environments (endemics), that they could quickly disa

Determine the luria''s testing methods, Determine the Luria's testing metho...

Determine the Luria's testing methods The choice of using items selected by Christensen to determine Luria's testing methods was, in retrospect, probably less crucial than the

Define functions of vitamin d, Define Functions of Vitamin D? Vitamin D...

Define Functions of Vitamin D? Vitamin D is required to maintain normal blood levels of calcium and phosphate, which are in turn needed for the normal mineralization of bone, m

Biology in ancient india, BIOLOGY IN ANCIENT INDIA - L A T E STONE ...

BIOLOGY IN ANCIENT INDIA - L A T E STONE AGE [10,000 - 20, 000 B.C) Man first cultivated wheat, barley, lentils & peas. In India rice was first cultivated at Meherga

Define endurance capacity by standard running tests, Define Endurance capac...

Define Endurance capacity by standard running tests? Endurance capacity, on the other hand, is measured by standard running tests in which time to exhaustion is taken as the en

What is the futile cycle, What is the futile cycle The futile cycle is ...

What is the futile cycle The futile cycle is avoided because covalent modification, by  phosphorylation, has opposite effects on  the  enzymes concerned with  the  synthesis  a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd