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Careful consideration of the bioreactor agitation and aeration system is required in order to maintain a homogeneous environment and provide sufficient oxygen transfer rates to meet cellular metabolic requirements.
Both agitation and aeration need to be considered together as they have an influence on the mechanical design of the fermenter, the oxygen transfer characteristics of the vessel and its power requirements.
There are a number of components that contribute to the aeration and agitation system efficiency including the height/diameter ratio. These are:
i. the impeller system (marine, flat-blade turbine etc) ii. the baffles (can also provide additional cooling capability) iii. the air sparger (ring, cross orifice, porous, nozzle) iv. the drive seal (mechanical, magnetic)
Q. Describe the term ‘Critical Insulation thickness'. What is its significance? Derive an expression for the critical insulation radius of a spherical system. A bar of square cr
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Creating 3-d solid models Two basic approaches to create solid models are : (i) Constructive solid geometry (CSG or c-rep), and (ii) Boundary representation (b-rep).
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Evaluate stress in fibre: Example, the matrix material can be stressed to its full strength of 80 MPa, calculate the allowable % of broken fibres. What will be the stress in f
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