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Careful consideration of the bioreactor agitation and aeration system is required in order to maintain a homogeneous environment and provide sufficient oxygen transfer rates to meet cellular metabolic requirements.
Both agitation and aeration need to be considered together as they have an influence on the mechanical design of the fermenter, the oxygen transfer characteristics of the vessel and its power requirements.
There are a number of components that contribute to the aeration and agitation system efficiency including the height/diameter ratio. These are:
i. the impeller system (marine, flat-blade turbine etc) ii. the baffles (can also provide additional cooling capability) iii. the air sparger (ring, cross orifice, porous, nozzle) iv. the drive seal (mechanical, magnetic)
Bucket conveyors are used to moves the granular powdered or liquid materials. The buckets may be mounted on a chain or a belt. The movement may be vertical or flat. The ver
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A 6 cm diameter rubber ball weighing 5 g is used to plug a 4 cm hole in the base of a tank. The tank is in use and is gradually emptying. At approximately what depth will the ball
Constructive Solid-Geometry Methods (CSG) Constructive models represent a solid as a combination of primitive solids. This modeling technique combine the volumes occupied by ov
A hollow mild steel tube 6 m long 4 cm internal diameter and 6 mm thick is used as a strut with both ends hinged. Determine the crippling load and safe load taking factor of safety
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A compound cylinder is made by shrinkage one cylinder of 120 mm external diameter and 20 mm wall thickness. The shrinkage allowance , based on radius , is 0.025 mm. If both cylinde
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