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Acetylcholine, a well known neurotransmitter, plays a critical synaptic role in the initial formation of memory. Chemical blockage of the acetylcholine receptors makes it harder to learn and remember even in healthy young people. Evidence for it comes from pharmacological studies conducted on human subjects wherein blockage of muscarinic cholinergic receptors by drugs such as scopolamine impaired the encoding of new memories. Conversely, drugs which activated nicotinic receptors enhanced the encoding of new information.
Similarly administration of scopolamine into the hippocampus impaired encoding of spatial memory. It has also been found that administration of drug that increases the level of acetylcholine in Alzheimer's disease (characterised of memory problems) improves memory by inhibiting the action of acetyl cholinesterase, an enzyme that breaks down acetylcholine and reduces its amount. Overall it can be said that decreased acetylcholine in the brain cause problems with memory function.
Would you expect the muscle fibers of the tongue to be striated or smooth? What about the muscle of the diaphragm/ Explain your answer.
Ritonavir (RTV, Norvir) Ritonavir is well absorbed from the gastrointestinal tract and at full doses potently inhibits HIV, but due to poor tolerability it is now used mainly
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Q. Discuss the colour coding rules for biomedical waste management and handling? Colour coding biomedical waste( management and handling) rules, 1998
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