Acetylcholine - long term potentiation, Biology

Assignment Help:

Acetylcholine, a well known neurotransmitter, plays a critical synaptic role in the initial formation of memory. Chemical blockage of the acetylcholine receptors makes it harder to learn and remember even in healthy young people. Evidence for it comes from pharmacological studies conducted on human subjects wherein blockage of muscarinic cholinergic receptors by drugs such as scopolamine impaired the encoding of new memories. Conversely, drugs which activated nicotinic receptors enhanced the encoding of new information.

Similarly administration of scopolamine into the hippocampus impaired encoding of spatial memory. It has also been found that administration of drug that increases the level of acetylcholine in Alzheimer's disease (characterised of memory problems) improves memory by inhibiting the action of acetyl cholinesterase, an enzyme that breaks down acetylcholine and reduces its amount. Overall it can be said that decreased acetylcholine in the brain cause problems with memory function.


Related Discussions:- Acetylcholine - long term potentiation

Conduct of perfusion-cardio pulmonary bypass, Conduct of Perfusion :  At t...

Conduct of Perfusion :  At the beginning of the bypass, the pump output is usually kept at 2.4 litres per meter per minute. On coming off bypass, the flow is gradually reduced til

Silver point and silver point removal-endodontics principles, Silver point:...

Silver point: -    Uses of silver point: ease of handing and placement, ductility, radiopacity,and have  some antibacterial activity. -    Lack of acceptable 3D seal of the ca

What is the type of reproduction that occurs in roundworms, What is the typ...

What is the type of reproduction that occurs in roundworms? What typical element do nematode sperm cells have? Nematodes reproduce sexually. The nematode sperm cell does not h

What is mefloquine, What is Mefloquine Mefloquine is taken once weekly,...

What is Mefloquine Mefloquine is taken once weekly, but recent reports of serious psychiatric adverse effects have prompted the manufacturer, along with the FDA, to strengthen

Human embryo, Human embryo: After fertilization the human embryo divide...

Human embryo: After fertilization the human embryo divides mitotically and develops two membranes: 1) Chorion 2) Amnion Functions of the membranes: i) Chorion : It

Zoology, anthropoda locomotion

anthropoda locomotion

What is joints in human biology, What is Joints Joints are locations...

What is Joints Joints are locations where two or more bones come together, or articulate. Bones are joined with varying degrees of rigidity. Joints may be fixed, as in the s

Endomyocardial biopsy, Endomyocardial biopsy helps in understanding that ca...

Endomyocardial biopsy helps in understanding that carditis can cause CCF in patients with rheumatic heart disease but frequency of diagnostic features on EMB is found only in 17 pe

What does a two-direction arrow show in a chemical equation, What does a tw...

What does a two-direction arrow show in a chemical equation? The oxygen atoms share two pairs of electrons, as every atom needs two more electrons to fill the orbitals of its o

Regulation of respiration, Regulation of Respiration Whenever the need...

Regulation of Respiration Whenever the need for oxygen in the body increases, ventilation of the respiratory organs also increases. In the same way whenever the level of oxyge

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd