What is the generation of clonal diversity

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Question

Immune System: Structure and Normal Function

1. What is the difference between the innate and adaptive immune system?

2. What are the cells of the immune system and where do they come from?

3. Review the different Myeloid-derived cells. What does each do?

4. Review the different Lymphoid-derived cells. What does each do?

5. How does the formation/development of B vs. T lymphocytes differ?

6. What is the difference between primary and secondary lymphoid structures? What is significant about the placement of secondary lymphoid structures?

7. Describe and compare the various "lines of defense" involved in an innate immune response.

8. What events can initiate a local inflammatory response?

9. If a pathogen manages to slip past an epithelial border without damage to tissue, what are the first cells that recognize it initiate an inflammatory response? By what mechanism is the inflammatory response triggered?

10. What are the vascular and cellular events of acute inflammation and in what sequence do they occur?

11. The process of inflammation tends to bring about some degree of damage to otherwise healthy local tissue. What cells are responsible for this "collateral damage" ? What inflammatory mediators are responsible?

12. What role do Mast Cells play in inflammation?

13. What are the relevant metabolites of Aracidonic Acid in relation to acute inflammation and what are their respective functions?

14. What is the complement system and what are the possible pathways by which it can be activated?

15. How does the complement system interact with both innate and acquired immunity?

16. Describe the events involved in chronic inflammation. What does it mean to say that chronic inflammation is always pathological?

17. What are the Major Histocompatibility Complex molecules? Which cells possess class I and II MHCs and what function do these molecules play in immunity?

18. What is the generation of clonal diversity?

Reference no: EM133948719

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