What is new about thrombopoietin

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Assignment:

National borders offer trivial impediment to infectious disease threats. In the highly interconnected and readily traversed global village of our time, one nation's problem soon becomes every nation's problem. Therefore, many of the strategies described above must be implemented worldwide, not just nationally, in order to have a true impact.

1. What is the meaning of the international normalized ratio (INR) blood test?

2. What is the cause of moderate thrombocytopenia in Bernard-Soulier syndrome? It is a qualitative defect not a quantitative platelet disorder.

3. What is new about thrombopoietin?

4. What is the rationale behind the use of desmopressin in bleeding disorders?

5. What effect does the contraceptive pill have on the blood fibrinogen level and on blood coagulability?

6. Does standard (unfractionated) heparin in doses of 10 000-15 000 units/day need monitoring?

7. Is there an antidote for low-molecular-weight heparin (LMWH)? Can Enoxaprin be used?

8. 1. What is the mechanism of the action of aprotinin? 2. What is the therapeutic window for aprotinin? 3. In a case of haemorrhagic stroke, how many days should aprotinin be prescribed for and what is the recommended dosage?

9. My question is, what are thrombophilia scan tests? Can we use these in patients on anticoagulant therapy?

10. In thromboembolic disorders, how is clopidogrel superior to aspirin?

Reference no: EM133860998

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