Possible adverse effects of folic acid fortification

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Possible adverse effects of folic acid (FA) fortification

Folic acid requires reduction via dihydrofolate reductase (DHFR) to be converted to tetrahydrofolate ?Rate-limiting step, DHFR has very weak activity in humans ?High doses of FA saturate DHFRun-metabolized folic acid ; explain this simply

Reference no: EM133841127

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