Polymorphism poor metabolism phenotypes

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Question

Your patient undergo genetic testing and found to have a CP2D6 polymorphism poor metabolism phenotypes. You know that the tricyclic anti-depressant medications are metabolized by CYP2D6 enzyme pathway. You plan on prescribing amitriptyline for your patient for depression. A starting dose of amitriptyline is 50-100mg daily at bedtime. Given the patient's poor metabolizer phenotype which of the following doses of Amitriptyline would be the appropriate dose for the patient to be started on?

Reference no: EM133975981

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