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Question: Ms. TS is a 35-year-old female admitted to the hospital for fever, chills, and pain in her side for 3 days. Dr. Hurt diagnoses bacterial peritonitis and wants to initiate vancomycintherapy. Ms. TS's height is 5'4", admission weight 62 kg, and serum creatinine1.4mg/dL. The vancomycin is to be infused over 1hour. Use expected pharmacokineticparameters based on average literature data and the patient's clinical history tocalculate
1. Calculate a vancomycin clearance for this patient.
2. Calculate a vancomycin Volume of distribution for this patient.
3. Calculate a vancomycin half-life for this patient.
4. It was decided to start Ms. TS on vancomycin (infused over 1 hr.) to maintain a trough concentration of 7.5 mg/L Calculate the initial vancomycin dose and suggest an appropriate dosing regimen
5. What will be a once daily vancomycin dose for this patient?
6. Once a daily dose of 1500mg is administered Q24 hours, what would be the predicted steady state vancomycin trough level for this patient?
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