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Define role of Vitamin K in controlling gene expression?
Prithrombin, a protein required for blood clotting is assembled with a large number of glutamic acid residues. In the presence of vitamin K, these residues are carboxylated, and this posttranslational change results in a dramatic increase in the calcium binding capacity of the resultant protein. Unless prothrombin can bind calcium, it cannot function in the clotting process. This is another example of how a nutrient can affect gene expression; in this instance, it is the expression of functional prothrombin. The site of the nutritional effect is that or posttranslational protein modification.
Bohr Effect Another important influence is the pH. Increase in carbon dioxide or other acids lowers the pH of plasma and shifts the dissociation curve to the right. At high ca
How do you draw in organic chemistry format a carbon double bonded to an oxygen atom when this carbon is the first carbon on a carbon skeleton of a molecule?
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