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Ornithine-urea cycle
The synthesis of urea (H2N.CO.NH2) from one molecule of CO2 and two of NH, occurs in the liver of ureotelic vertebrates by a metabolic pathway known as the ornithine-urea cycle, discovered by Kreb and Hensleit in 1932. This is a cyclic pathway that involves five enzyme-catalised reactions.
Figure: Ornithine-urea cycle
You can see in Figure that this cycle has five steps :
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