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Define role of Leptin in controlling gene expression?
Leptin is a protein product (containing 167 amino acids) of the ob gene expressed exclusively in the adipose tissue. This protein molecule functions as an afferent signal in a negative feedback loop, centred in the hypothalamus, regulating the size of the adipose tissue mass.Leptin has been shown to modulate the synthesis of neuropeptides, particularly Neuropeptide Y (NPY) that regulates food intake. Increases energy expenditure as indicated by animal experiments. Leptin induced weight loss is completely specific for adipose tissue. While feeding does not appear to modulate leptin expression, fasting acutely decreases plasma leptin concentration. In general, obese humans have high leptin levels and the available data suggest that human obesity is likely to be associated with insensitivity to leptin.
what is the excretory organ of lizard
Definition of old age? The exact timing of the onset of the ageing process cannot be ascertained because the effect of age varies among different individuals. However, the chr
Q. Type one Diabetes Mellitus? Type 1 DM occurs in children and adolescents (6-14 yrs). In this disease, the body makes little or no insulin. Daily injections of insulin are ne
Define Colorimetric Method - 2, 4 Dinitrophenylhydrazine Method? We shall use this method in estimating vitamin C in a given sample in the laboratory. Here, let us look at the
Asymmetric carbon atom : a carbon atom attached with four different groups or atoms.
Define Clinical Significance and Risk Factors for Drug-Nutrient interactions? We are already aware of the fact that poor nutritional status can impair drug metabolism and the d
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Q How do cells get energy for their functioning? Cells get energy for their metabolic reactions from the breaking of organic molecules with high energetic content. This energy
y it was critised
Are the alleles of a gene essentially originated one from the father and the other from the mother? Are there exceptions? It is natural so that alleles have come one from the m
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