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What is coronary disease?
Coronary disease, or coronary insufficiency, is a disease in which there is total or partial obstruction of one or more of the arteries that irrigate the heart musculature, i.e., obstruction of the coronary arteries. The disease is formed by slow and gradual formation of atheroma plaques inside the coronaries. The fatty plaques grow and block the flow of blood, a process known as atherosclerosis (do not confuse with arteriosclerosis which is the hardening of the arteries generally cause by chronic high blood pressure).
What are some of the presumed target substrates for cyclin-dependent kinases?
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