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Synthesis of Polyamine
As the name of this class of compounds suggests, polyamines have several amino groups replacing hydrogen usually in alkyl chain e.g., putrescine is 1, 4-diamino butane. Polyamines are known to have significant effect on the stability of various conformational states of RNA and DNA and are often associated with important phases in cell division cycle. They occur in microbes, plants and animals. In plants, they have been implicated to help in developing stress tolerance. Cereal leaf segments exposed to osmotic stress or low pH show up to 60 fold rise in putrescine level.
Figure: Molecular structure of common polyamines
Production of haploids by tissue culture,
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