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Define Role of Glucose-6-phosphate dehydrogenase - Gene Expression?
Glucose-6-phosphate dehydrogenase (G6PD) is another enzyme involved in lipogenesis that is regulated by dietary factors. G6PD activity is needed in all cell types for the production of NADPH and for the control of carbon flow through the pentose phosphate pathway. G6PD catalyzes the first reaction of this pathway, oxidizing glucose-6- hosphate to 6-phosphogluconolactone , and in the process reducing NADP' to NADPH+ H+. This reaction, you may recall studying, is the rate-determining step of the oxidative portion of the pentose phosphate pathway. Together with 6- phosphogluconolactone dehydrogenase, the enzyme provides NADPH for reductive biosynthetic reactions, such as fatty acids, cholesterol and amino acids and for the maintenance of reduced glutathione concentration. In addition, it regulates the rate of glucose conversion to ribose-5-phosphate, the precursor for nucleotide biosynthesis. G6PD expression is regulated by hormonal and nutritional factors in a few tissues such as the liver and mammary glands.
Long-term starvation decreases the activity of the enzyme, while re-feeding with a fat free; high-carbohydrate increases the activity to an amount greater than in the "normal" fed state. Glucose and fructose increase activity to a larger extent than starch and the response is greater with fructose than with glucose.
Determine How Nutrition used to Prevent Dehydration? Maintaining optimal hydration status along with sufficient muscle glycogen stores delays the onset of fatigue and enables
Zoonotic Diseases The term zoonosis (zoonoses, plural) was coined by Rudolf Virchow to describe the disease transmitted from animal to man and vice versa. Zoonoses have been de
The process of meiosis in animals is called gametogenesis .It takes place in the testis in male and ovary in female. Gametogenesis is divided into spermatogenesis (formation of
what is its working
Determine Energy requirements of school children and adolescents? Table depicts the energy requirements of school children and adolescents, as recommended by ICMR (1990).
Monoclonal Antibody is an antibody with quite specific and often unique binding specificity which is secreted by the biologically cloned line of plasmacytoma cells in the absence
ADA PTATIONS IN SKELETON FOR UPRIGHT POSTURE - 1. Foramen magnum is directed downward so that the head may rest vertically on the vertebral column. 2. Four curves
In shorthorn cattle, the coat colours red or white are controlled by a single pair of alleles. A calf which receives the allele for red coat from its mother and the allele for whit
How does the Cornea work, I heard that it is like a motor, however i''m not too sure... because a motor is in vehicle and has piston, and the Cornea is in our eyes and... Well does
Healthy human female X is 25 years old and not pregnant. During the postovulatory phase of X's menstrual cycle, A. there are high blood plasma levels of LH and FSH.
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