Rational in individual patient, Biology

Assignment Help:

Thiazide diuretics have been accepted as the primary foundation of antihypertensive therapy. The basis of this choice is that, apart from their primary hypotensive effect, they enhance the efficacy of other hypotensive drugs. It has been observed that most of the hypertensive patients would require 2 or more drugs for optimal control. Usually another drug from a different class can be added when BP is more than 20/10 above the goal. The drugs can be administered either separately or as fixed dose combinations. The presence of comorbid conditions should determine the choice of specific classes of hypotensive drugs.

a) Ischemic Heart Disease

In patients with hypertension and stable angina the drug of choice is usually a beta-blocker, with or without a long acting calcium channel blocker. In unstable angina, a beta-blocker, diltiazem and ACE inhibitors or an ARB are the preferred ones. In post infarction states beta-blockers and ACEI/ARB are the choices.

b) Heart Failure

With the current interest in diastolic heart failure there is a greater interest in the management of diastolic dysfunction usually detected on echocardiography. Beta-blockers and ACEI/ARB are the choices. Diuretics are not recommended since they decrease the LV filling pressure. In early systolic dysfunction, ACE/ARB are given. In florid heart failure it has to be diuretics, aldosterone antagonists, ARB/ACEI are recommended.

c) Diabetic with Hypertension

ACEI and ARBs are first choice since they have been found to retard the progression of diabetic nephropathy and may reduce albuminuria. Other drugs can be added to obtain the target BP of 130/80.


Related Discussions:- Rational in individual patient

Implementation of nursing care for thalassemia patient, Implementation of N...

Implementation of Nursing Care   Prepare the Patient for Diagnostic Evaluation Your role as a nurse is to provide continuing support to the child and family during diagnos

What are the cells that form the cartilaginous tissue, Q. What are the cell...

Q. What are the cells that form the cartilaginous tissue? The main cells of the cartilages are the chondrocytes originated from the chondroblasts that secrete the intersticial

Explain what is periodontal condition, Explain what is Periodontal Conditio...

Explain what is Periodontal Condition? If intact attachment apperatus without pocket, time is critical direction toward non-surgical repair to prevent periodontal breakdown

Cell cycle, What can stop a normal cell from growing?

What can stop a normal cell from growing?

Human physiology, Carbohydrates and proteins question #Minimum 100 words a...

Carbohydrates and proteins question #Minimum 100 words accepted#

Endocrine glands - kidney, KIDNEY S - Origin . They develop from the ...

KIDNEY S - Origin . They develop from the mesoderm of the embryo. The kidneys secrete three hormones: renin, erythropoetin and calcitriol. (i) Renin . Whenever the rat

Explain what is cyanosis and polycythemia, Explain what is Cyanosis and pol...

Explain what is Cyanosis and polycythemia? Cyanosis and Polycythemia: Central cyanosis involving the mucous membranes and trunk along with the lips and extremities in absence

Explain the working of skeletal muscle, Explain the working of Skeletal Mus...

Explain the working of Skeletal Muscle? Skeletal muscle is under voluntary control and is responsible for voluntary movements of body parts. Skeletal muscle is also called stri

What is triacylglycerols, A triglyceride TG, TAG, triacylglycerol or triacy...

A triglyceride TG, TAG, triacylglycerol or triacylglyceride is an ester derivative from glycerol and three fatty acids. There are various triglycerides: depending on the oil source

How many weeks are required to recover after blood donation, When a human d...

When a human donor gives a pint of blood, it generally requires how many weeks for body RESERVE of red corpuscles to be replaced? Is it: a) 7 week b) 3 weeks c) 1 weeks

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd