Rational in individual patient, Biology

Assignment Help:

Thiazide diuretics have been accepted as the primary foundation of antihypertensive therapy. The basis of this choice is that, apart from their primary hypotensive effect, they enhance the efficacy of other hypotensive drugs. It has been observed that most of the hypertensive patients would require 2 or more drugs for optimal control. Usually another drug from a different class can be added when BP is more than 20/10 above the goal. The drugs can be administered either separately or as fixed dose combinations. The presence of comorbid conditions should determine the choice of specific classes of hypotensive drugs.

a) Ischemic Heart Disease

In patients with hypertension and stable angina the drug of choice is usually a beta-blocker, with or without a long acting calcium channel blocker. In unstable angina, a beta-blocker, diltiazem and ACE inhibitors or an ARB are the preferred ones. In post infarction states beta-blockers and ACEI/ARB are the choices.

b) Heart Failure

With the current interest in diastolic heart failure there is a greater interest in the management of diastolic dysfunction usually detected on echocardiography. Beta-blockers and ACEI/ARB are the choices. Diuretics are not recommended since they decrease the LV filling pressure. In early systolic dysfunction, ACE/ARB are given. In florid heart failure it has to be diuretics, aldosterone antagonists, ARB/ACEI are recommended.

c) Diabetic with Hypertension

ACEI and ARBs are first choice since they have been found to retard the progression of diabetic nephropathy and may reduce albuminuria. Other drugs can be added to obtain the target BP of 130/80.


Related Discussions:- Rational in individual patient

State about dental implant reconstruction, State about Dental implant recon...

State about Dental implant reconstruction Dental implant reconstruction requires a thorough knowledge and understanding of the various strategically important anatomic landmark

Malthusian theory of population growth, In 1798, British economist and demo...

In 1798, British economist and demographer Thomas Robert Malthus, published his' essay on population' in which he stated that: 1.      Population increases in a geometric rat

Use of gloves as personal protective equipment, Q. Use of Gloves as persona...

Q. Use of Gloves as personal protective equipment? Gloves are task specific. The different types of gloves worn in the dental office are: i) Examination gloves ii) Over o

Unitary explanation for protein synthesis, Q. Why is the concept of a singl...

Q. Why is the concept of a single gene as ultimateunit of inheritance inadequate to provide a unitary explanation for protein synthesis, recombination and mutation? Answer:

Write details of botanical source, Question 1: Write details of Botanic...

Question 1: Write details of Botanical source, common name, part of plant used, chemical constituents and uses for the given drugs: a) Momordica charantia b) Moringaoleifera c

Phylum arthropoda, PHYLUM ARTHROPODA Definition and Introduction ...

PHYLUM ARTHROPODA Definition and Introduction Bilateral  and protostomial eucoelomate  eumetazoa with metamerically  segmented  and each  segment bearing a pair  of  join

Cost due to damage to equipment, Cost due to Damage to Equipment Cost ...

Cost due to Damage to Equipment Cost due to Damage to Equipment, Property etc. Tooling may have to be redesigned, adding cost. Cost due to reduced output and delay

Explain results of abdominal aneurysm surgery, Explain Results of  abdomin...

Explain Results of  abdominal aneurysm surgery? Results:  For ascending aorta replacement, the hospital mortality varies from 0 to 9 per cent. Aortic arch has higher risk of

Why did it not drop more give reason, Mr. Smith read that cholesterol was b...

Mr. Smith read that cholesterol was bad for his health so he eliminated all foods and food products containing this molecule. He later found that his cholesterol level dropped only

Respiration, how energy enters and then flows through a biological system

how energy enters and then flows through a biological system

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd