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Pathophysiology
Infective endocarditis occurs when turbulence within the heart allows causative organism to infect previously damaged valves or other endothelial surfaces.
Vegetations consisting of fibrin, leukosytes, platelets and microbes adhere to the valve surface or endocardium. The loss of portions of the friable vegetations into the circulation result in embolization. Infection spread to heart valves leads to valvular incompetence, CHF, generalized myocardial dysfunction and sepsis.
Describe Inflammation and Atherosclerosis ? It has recently been stated that atherosclerosis is clearly an inflammatory disease and does not result simply from the accumulatio
Explain Rifaximin Rifaximin (Xifaxan - Salix), a non-absorbed oral antibiotic derived from rifampin (Rifadin, and others), has been approved by the FDA for treatment of travele
CONDUCTIO N OF IMPULSE - IN NON-MYELINATED AXONS - The impulse moves along the axon as local effect by altering the permeability of neighbouring Na + channels and af
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