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Last observation carried forward is a technique for replacing the observations of the patients who drop out of the clinical trial carried out over a time period. It consists of substituting for each missing value the subject's last available assessment of same type. Though widely applied, particularly in the pharmaceutical industry, its use is very limited since it makes very improbable assumptions about the data, for instance, that the (unobserved) post drop-out response are frozen at the last observed value.
How large would the sample need to be if we are to pick a 95% confidence level sample: (i) From a population of 70; (ii) From a population of 450; (iii) From a population of 1000;
This is an attempt to measure the suffering caused by the illness which takes into the account both the years of the potential life lost due to the premature mortality as well as t
Quantalassay: The experiment in which the groups of subjects are exposed to the different doses of, generally, a drug, to which the particular number respond. Data from such type
Standardise the following arguments, which involve counter-arguments Some educators have argued that the increasing use of the internet by children and teenagers will have a be
Protocol is the formal document outlining the proposed process for carrying out the clinical trial. The basic features of the document are to study the objectives, patient selecti
The statistical methods for estimation and inference which are based on a function of sample observations, probability distribution of which does not rely upon a complete speci?cat
A directed graph is simple if each ordered pair of vertices is the head and tail of at most one edge; one loop may be present at each vertex. For each n ≥ 1, prove or disprove the
Randomization tests are the procedures for determining the statistical significance directly from the data with- out recourse to some particular sampling distribution. For instanc
You and your team have been hired as strategic consultants by the hugely successful retailer known as “Cutie Pie”. The company sells many products, although one product in particul
Clinical vs. statistical significance : The distinction among results in terms of their possible clinical importance rather than simply in terms of their statistical importance. Wi
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