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Knock-out experiment is a method for deleting, mutating or otherwise inactivating the gene in a mouse. This laborious technique involves transfecting a crippled gene into cultured embryonic stem cells, searching through thousands of the resulting clones for one in which the crippled gene exactly replaced the normal one (by the homologous recombination), and inserting that cell back into the mouse blastocyst. The resulted mouse is chimaeric but, if you are lucky enough (and if you've gotten this far), its germ cells will carry the deleted gene. A few rounds of causious breeding can then produce progeny in which both the copies of the gene are inactivated.
Sources of Water Pollution There are natural sources of water pollutants such as mineral ores from rocks, chemicals, from mines and gases from atmosphere. But we will conside
What is the difference between bryophytes and tracheophytes? Bryophytes are nonvascular plants (mosses, hornworts, liverworts), i.e., they do not have a conductive system for t
Define Factors that Affecting the Calcium Absorption? It is a well known fact that the amount of calcium that we eat need not be the amount of calcium that gets absorbed. The d
Q. Complications in celiac disease? Patients with severe form of celiac's disease for long period are at risk for several complications mainly due to nutrient absorption probl
Explain Hair changes - clinical signs of kwashiorkor? In kwashiorkor, the hair loses its healthy sheen and becomes silkier and thinner. It takes coppery red colour (referred to
Animal Biotechnology: Animal cell cultures have been and are being generate important products based on their genetic information or due to genes transferred into them (transge
Enumerate about the Wisconsin Card Sorting Test Verbal memory, non verbal memory etc. are tested through the presentation of stimuli such as verbal learning test, selective rem
In shorthorn cattle, the coat colours red or white are controlled by a single pair of alleles. A calf which receives the allele for red coat from its mother and the allele for whit
Collection of Cerebro-spinal Fluid (CSF) Examination of the CSF is one of the most useful laboratory procedures in neurological diagnosis. Four types of punctures ma
Crustacea The Crustacea show a great morphological diversity of appendages which may be grouped into three categories, cephalic, thoracic and abdominal. Their appendages are c
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