Intention-to-treat analysis, Advanced Statistics

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Intention-to-treat analysis is the process in which all the patients randomly allocated to a treatment in the clinical trial are analyzed together as representing that particular treatment, whether or not they completed, or even received it. At this time the initial random allocation not only governs the allocated treatment, it governs there and then how the patient’s data will be further analyzed, whether or not the patient actually receives prescribed treatment. This technique is adopted to prevent disturbances to the prognostic balance attained by randomization and to prevent the possible bias from permitting compliance, a factor often related to results, to determine groups for comparison. 


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