Randomized consent design, Advanced Statistics

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Randomized consent design is the design at first introduced to overcome some of the perceived ethical problems facing clinicians entering patients in the clinical trials including random allotment. After the patient's eligibility is established the patient is randomized to one of the two treatments A and B. Patients randomized to the treatment A are approached for patient consent. The patients are asked if they are willing to receive the therapy A for their illness. All the potential risks, benefits and treatment options are discussed. If patient agrees for it, treatment A is given. If the patient does not agree, the patient receives treatment B or some other alternative treatment. Those patients who are randomly assigned to group B are similarly asked about the treatment B, and transferred to the alternative treatment if consent is not provided.


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