Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Cancer lung, Cancer Lung Incidence of cancer lung is more in persons ...

Cancer Lung Incidence of cancer lung is more in persons who smoke. Environmental and industrial pollution is also a risk factor in the increase in incidence. Clinic

Cleavage and gastrulation, Cleavage and Gastrulation Eventually, one s...

Cleavage and Gastrulation Eventually, one spermatozoon fuses with the ovum to r restore the diploid genomic condition and activates all the potentials in the fertilized egg ce

Telementoring, TELEMENTORING Telementoring is used by a nursing teache...

TELEMENTORING Telementoring is used by a nursing teacher providing training/advice? to another nurse consultant at a remote site. The Internet has made teleconsultation and t

What are plasmids, What are plasmids? The Plasmids are circular DNA mol...

What are plasmids? The Plasmids are circular DNA molecules present in the genetic material of some bacteria. They may perhaps contain genes responsible for bacterial resistance

Relate fibro-osseous retention and osseointegration, Fibro-osseous Retenti...

Fibro-osseous Retention V/S Osseointegration Fibro-osseous retention is the tissue to implant contact interposition of the healthy, dense collagenous tissue between the implant

What is an antigen, Q. What is an antigen? Antigen is any substance, in...

Q. What is an antigen? Antigen is any substance, infectious or particle agent recognized as foreign to the body. The contact of the antigen with the body promotes a defense rea

Draw a diagram of transverse section of mammalian bone, Draw a diagram of t...

Draw a diagram of transverse section of mammalian bone and label the following parts in it: (i) Haversian canal (ii) Lacuna containing osteocytes (iii) Canaliculi

Sample titration for determination of iodine number of lipid, Define Sample...

Define Sample titration for Determination of the Iodine Number of Lipids? With a clean dry pipette, accurately measure 0.3 mL of oil into a clean and dry iodination flask (Dupl

What are plant cell vacuoles, What are plant cell vacuoles? What are their ...

What are plant cell vacuoles? What are their functions? How is the covering membrane of the vacuoles called? Ans) Plant cell vacuoles are cell structures delimited by membranes

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd