Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

What is bilateral symmetry system, What is Bilateral Symmetry system? T...

What is Bilateral Symmetry system? To review: all animals besides the sponges (Phylum Porifera) belong to the Eumetazoa. There are two groups within the Eumetazoa that possess

Ecology, importance of pyramid of energy to the ecologist

importance of pyramid of energy to the ecologist

Do octopus and squids have exoskeleton, Do octopus and squids have exoskele...

Do octopus and squids have exoskeleton? Octopus and squids normally do not produce external shell (some squid species can have an internal shell). One cephalopod group, the nau

Define nutritional requirements of fats and oils, Define Nutritional Requir...

Define Nutritional Requirements of Fats and Oils? As with the other macronutrients, we do compute requirements of visible fats too for all age groups and give guidelines for se

Which of these lists contains the four postulates, Which of these lists con...

Which of these lists contains the four postulates  of natural selection? Which of these lists contains the four postulates of natural selection? Uniform population, heritable trait

Enumerate the term - pathognomic sign, Enumerate the term - pathognomic sig...

Enumerate the term - pathognomic sign A comprehensive assessment ideally uses all four approaches. Some forms of specialised assessment rely heavily on pathognomic signs, behav

What is the concept of universality of the genetic code, What is the concep...

What is the concept of universality of the genetic code? What are the exceptions to this universality? The genetic code is universal because the rules of protein codification b

Phototheraphy and exchange transfusion, PHOTOTHERAPHY AND EXCHANGE TRANSFUS...

PHOTOTHERAPHY AND EXCHANGE TRANSFUSION: This section will enable you to acquire skills related to phototherapy and exchange transfusion. You will also review the indication

Early pre-operative care of cardiac surgical patient, Early Pre-operative C...

Early Pre-operative Care   1. Admission of patient-usual admission procedure to be completed. 2. Assessment of the patient. 3. History 4. Physical examination

Define about the growth and development in children, Define about the Growt...

Define about the Growth and development in children? Growth and development in children can be studied under the following heads: . • Changes in physical development and bod

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd