Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Enumerate the history of neuropsychological, Enumerate the history of neuro...

Enumerate the history of neuropsychological The typical neuropsychological exam begins with a careful history taking. Areas of interest include: Medical history of patie

Australopithecines, The first ever australopithecine fossil was found in 19...

The first ever australopithecine fossil was found in 1924 at Taung, South Africa. It was the skull of a 6 year old child showing a mixture of human and ape like features. This a

Digestive system of class asteroidea, Digestive System of Class Asteroidea ...

Digestive System of Class Asteroidea Most asteroids are scavengers or carnivores and feed on snails, bivalves, polychaets, other echinoderms, fish, sponges, sea anemones and p

State in detail about dark adaptation, State in detail about Dark Adaptatio...

State in detail about Dark Adaptation Dark adaptation is a phenomenon by which retina and pupil react to decreased illumination. Test is performed using Goldmann-Weeke's adapto

Explain the anaesthesia and analgesia, Explain the Anaesthesia and Analgesi...

Explain the Anaesthesia and Analgesia Most implant surgery can be carried out under local anaesthesia, although some patients will require sedation or general anaesthesia. The

Define advantages of direct microscopic count, Define Advantages of Direct ...

Define Advantages of Direct Microscopic Count? 1. It is easy, inexpensive and relatively quick method. 2. It gives information regarding size and morphology of microorganism

Procedure for preparation of selective & differential medium, Procedure for...

Procedure for Preparation of Selective and Differential Medium Now prepare the MacConkey agar medium following the steps given herewith: 1. Weigh and dissolve all ingredient

Tautomeric shifts, The original DNA sequence when ,transcribed and translat...

The original DNA sequence when ,transcribed and translated would yield five successive valine residues. But the altered sequence would correspondingly read one aspartate and four s

Help, A climate classification system divides regions according to _____?

A climate classification system divides regions according to _____?

Marine biomes, The marine biomes consist of the earth's oceans and its asso...

The marine biomes consist of the earth's oceans and its associated areas like the shorelines, islands, reefs and estuaries. The marine waters contain about 3.5 percent salt, mostly

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd