Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Zoology, explain in detail various types of epithelial tissue

explain in detail various types of epithelial tissue

Sticky sweet method-endodontics principles, Sticky sweet method Richwi...

Sticky sweet method Richwil crown and bridge remover -It is a resin block of water-soluble , like a stick sweet -It is first softened in hot water -Placed on the restorat

.rRNA , rRNA structure and synthesis assignment

rRNA structure and synthesis assignment

Explain about the cyanocobalamin, Explain about the Cyanocobalamin (vitamin...

Explain about the Cyanocobalamin (vitamin B 12 )? Vitamin B 12 (cobalamin, cbl) is a unique vitamin in human nutrition, since its malabsorption leads to the fatal syndrome of

What proportion of the offspring, A laboratory mouse homozygous for an RFLP...

A laboratory mouse homozygous for an RFLP marker is mated to a wild mouse that is heterozygous for that marker. One of the heterozygous individuals resulting from this cross is mat

Monitoring of risk management, Monitoring of risk management Assessment...

Monitoring of risk management Assessment of effectiveness  of measures taken, and review risk  management  and/or assessment,  as  necessary. The outcome of the risk evaluation

Use values of biodiversity, Despite its importance, determining the value o...

Despite its importance, determining the value or worth of biodiversity is complex and often a cause for debate. This is largely due to the fact that the worth placed on biodiversit

What is the initial maintenance steps of implants, Initial Maintenance Step...

Initial Maintenance Steps of implants It is very essential, that from the beginning of the patient interaction regarding the implant therapy, through the diagnosis and planning

What is the essential concepts of endosseous healing, Essential Concepts of...

Essential Concepts of Endosseous healing 1) Osteoblast is the prime bone matrix synthesizing cell. Like most secretory cells, osteoblasts are polarized cells, and the direction

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd