Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Modern biology, Modern Biology Increasing advancement in biotechnology ...

Modern Biology Increasing advancement in biotechnology has brought about a veritable explosion of Biological knowledge since early 1950s.This vast modern biological information

Monitoring therapy for endocarditis, Within a week after initiation of effe...

Within a week after initiation of effective antimicrobial therapy, almost 75 per cent of patients with IE, including those with PVE, are afebrile and 90 per cent have defervesced b

Tissue culture, Note on production of haploid by tissue culture.

Note on production of haploid by tissue culture.

What is the difference between a hormone and a morphogen, What is the diffe...

What is the difference between a hormone and a morphogen? How do they act and what type of development do they control?

What is an endospore - staining strategies, What is an endospore? An en...

What is an endospore? An endospore is a specialized, highly resistant, dormant structure formed within the vegetative cell of some bacteria e.g. Bacillus (rod), Clostridium (ro

Explain lipoprotein excess, Explain Lipoprotein (Lp(a) Excess ? While c...

Explain Lipoprotein (Lp(a) Excess ? While cholesterol and triglycerides are important lipid risk factors, another lipoprotein factor called Lipoprotein (a) is thought to play a

What is the formula for photosynthesis, What is the formula for photosynthe...

What is the formula for photosynthesis? H 2 O + 6CO 2 + Light Energy ----> C 6 H 12 O6+ 6O 2 6 molecules of water + 6 molecules of carbon dioxide --->1 molecule of glucose

What are flavanols, What are Flavanols? Examples are catechin and epica...

What are Flavanols? Examples are catechin and epicatechin. You may have heard of the benefits of tea. Some of them are due to gallic acid, which is combined with epicatechin. F

Nervous system and nerve cells, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd