Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Megasporogenesis, Megasporogenesis One of the nucellar cells situ...

Megasporogenesis One of the nucellar cells situated subjacent to the epidermis differentiates into the primary archesporial cell. This cell is larger than the adjacent ce

Air and Noise Pollution, Photochemical smog results from automobile polluta...

Photochemical smog results from automobile pollutants reacting with what?

Effect on water bodies - dissolved oxygen (do), Effect on Water Bodies - Di...

Effect on Water Bodies - Dissolved Oxygen (DO) Most aquatic, organisms respire with oxygen dissolved in water. The quantity of dissolved oxygen in a unit volume of aerated wa

Reptiles - regeneration in vertebrates, Reptiles - Regeneration in Vertebra...

Reptiles - Regeneration in Vertebrates Among reptiles, the lizards like the Gecko Hemidactylus flaviviridis and Anolis carolinensis can again generate their tail, following au

How much proteins should be taken for management of obesity, How much Prote...

How much Protein should be taken for Management of Obesity? Adequate amount of proteins should be included in the diet to ensure proper metabolism and prevent weakness which is

Digestive system - liver, LIVE R (HEPAR) - Largest gland of body. W...

LIVE R (HEPAR) - Largest gland of body. Weighing 1.6 kg. Form 1/40 of the body weight. Bio-chemical laboratory. Bussiest part in whole river of life. Dark reddish brown

International support to control hpai and other tads, International support...

International support to control HPAI and other TADs In 2008, a new global approach called "One World, One Health" was defined by the four international technical agencies, i.e

What is logic of the transfusional compatibility abo blood, What is the lo...

What is the logic of the transfusional compatibility concerning the ABO blood group system? A transfusional compatibility for the ABO system takes into account the antigens pre

Type of skull, what type of skull does amphibians possess in general?

what type of skull does amphibians possess in general?

Sql''s fifth concept - null, SQL's Fifth Concept - NULL Unfortunately...

SQL's Fifth Concept - NULL Unfortunately, SQL embraces a fifth concept, called NULL, an apparently simple little thing but one that has pervasive effects on our usual underst

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd