Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Nutritional management of steatorrhoea, Q. Nutritional management of steato...

Q. Nutritional management of steatorrhoea? The Nutritional management of steatorrhoea should focus on the following: • Plenty of rest and relaxation and avoid stress •

Spermatogonia - spermatozoa, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 Spermatogonia - Spe

How can heart be affect, How can Heart be affect Heart may be affected ...

How can Heart be affect Heart may be affected in two ways. One of the complications of diabetes is autonomic dysfunction which may disturb rhythm of heart beat and may lead to

Explain innate immunity, Distinguish among epimorphic and morphallactic reg...

Distinguish among epimorphic and morphallactic regeneration, giving single example of each. Explain innate immunity. Name and explain the category of barrier which includes mac

Explain the principles of taxonomy, Explain the Principles of Taxonomy? ...

Explain the Principles of Taxonomy? The goal of taxonomy is to develop a workable classification that reflects evolutionary relationships and provides identification and no

Chromosome partitioning depends on polymerization state, Chromosome partiti...

Chromosome partitioning depends on changes in the polymerization state of bacterial proteins that are functionally analogous to what eukaryotic protein?

Why do sharks need to agitate their body to swim, How dissimilar are the sw...

How dissimilar are the swimming strategies in osteichthyes and in chondrichthyes? Why do sharks need to agitate their body to swim while bony fishes do not? Bony fishes have a

Things to do before an earthquake for minimizing losses, Things to do-  We ...

Things to do-  We ought to aide by earthquake resisting building codes during construction and retrofitting of existing buildings. We should have a first AID box handy and learn

What is the ph inside the stomach, What is the pH inside the stomach? Why i...

What is the pH inside the stomach? Why is there a need to keep that pH level? How is it maintained? Which are the cells that produce that pH? The normal pH of the gastric juice

Describe fourth heart sound in details, Describe Fourth Heart Sound in deta...

Describe Fourth Heart Sound in details? S 4 is generated during the atrial-filling phase. It is a low frequency event. LVS, is best heard over apex. Mechanism of S 4 generat

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd