Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

To study if bacteria grow better where it is warm or cold, To study if bact...

To study if bacteria grow better where it is warm or cold Again inoculate two sterile dishes. Label one 'warm'  and the other 'cold'. Place the 1st dish in a dark warm place an

Determine the modification of food starches, Modification of Food Starches ...

Modification of Food Starches Positive attributes of starches can be greatly improved and/or negative characteristics diminished by slight and relatively simple modifications.

Explain about the macro minerals, Explain about the Macro Minerals? Pre...

Explain about the Macro Minerals? Previously we learnt about the structure, properties, deficiencies/toxicity and recommended dietary intakes of several vitamins. In this unit,

State the law of independent assortment, (a)State the law of independent as...

(a)State the law of independent assortment. (b )Using punnett square demonstrate the law of independent assortment in a dihybrid cross including two heterozygous parents.

What do you mean by tympanum, Q. What is the tympanum? In which part of the...

Q. What is the tympanum? In which part of the ear is it located and what is its function? The tympanum (or ear drum) is a membrane located in the middle ear just after the audi

What are the benefits of soil testing, What are the benefits of Soil testin...

What are the benefits of Soil testing Soil testing is done to assess the nutrient supplying capacity of the soil. The data obtained as a result of  testing is useful for recom

Why is the cerebellum more developed in mammals, Why is the cerebellum more...

Why is the cerebellum more developed in mammals that jump or fly? The cerebellum is the major brain structure that coordinates the movement and the equilibrium of the body. For

Define essentiality of vitamins for growth of micro-organism, Define Essent...

Define Essentiality of Vitamins for Growth of Micro-Organism Vitamins are also essential in small amounts for cellular activities and growth. These are also the coenzymes for a

Define obligatory nitrogen losses, Define Obligatory Nitrogen losses? T...

Define Obligatory Nitrogen losses? The Committee estimated the total obligatory nitrogen losses through faeces, urine, skin and other miscellaneous routes in adult men as 2.0 m

Zoonoses disease-chikungunya, Chikungunya Chikungunya, a metazoonosis,...

Chikungunya Chikungunya, a metazoonosis, is caused by chikungunya virus belonging to genus Alphavirus of the family Togavirideae. The virus is transmitted by infected mosquito

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd