Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

How can the visual deficiencies known as myopia, How can the visual deficie...

How can the visual deficiencies known as myopia and hypermetropia be optically explained? Myopia is the visual condition in which the images are produced before (in front of)

Define polyacrylamide gel electrophoresis (page), Define Polyacrylamide gel...

Define Polyacrylamide gel electrophoresis (PAGE)? Acrylamide gel has the advantage over starch in that it is easier to prepare and is more inert, the pore size can be varied in

Foraminifera, Foraminifera is the single-celled protists which secrete a s...

Foraminifera is the single-celled protists which secrete a shell or test. This is the accumulations of the shells of dead foraminifera and the other microscopic sea creatures form

Can you explain about cardiomyopathies, Q. Can you explain about Cardiomyop...

Q. Can you explain about Cardiomyopathies? Cardiomyopathy is a primary disorder of heart muscle that may cause cardiac dysfunction and is not related to any obvious disease pr

Explain in detail about working of heart, Explain in detail about working o...

Explain in detail about working of heart Heart has four chambers. Two upper chambers are called atria. Two muscular lower chambers are called ventricles. The right and left

Locomotory structures, Locomotory Structures Annelids possess three k...

Locomotory Structures Annelids possess three kinds of locomotory structures, namely parapodia, setae and suckers. Parapodia are segmentally arranged, lateral, hollow extensio

Explain algae have cell wall, Algae have cell wall made up of: 1. Cellul...

Algae have cell wall made up of: 1. Cellulose, galactans and mannans 2. Hemicellulose, pectins and proteins 3. Pectins, cellulose and proteins 4. Cellulose, hemicellulo

Define oral rehydration for treatment for pem, Define Oral rehydration for ...

Define Oral rehydration for treatment for pem? Since diarrhoea is very common in severe PEM, correction of dehydration is the first step in the treatment. Homemade (salt-sugar

Gametogenesis - human development, Gametogenesis - Human Development G...

Gametogenesis - Human Development Gametogenesis as you are responsive is the process of formation and development of specialized reproductive cells, ova in females and sperms

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd