Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Define beneficial effects of functional foods, Define beneficial effects of...

Define beneficial effects of functional foods? Several beneficial effects of functional foods have been reported, which include effects such as antioxidant, anticarcinogenic, b

Explain the classification of malignant tumors, Explain the Classification ...

Explain the Classification of Malignant Tumors Malignant tumors can be classified as: Carcinomas: These tumors arise from the epithelial lining (the squamous cells) e.g. ski

What is mendels second law, What is Mendel's second law? Mendel's seco...

What is Mendel's second law? Mendel's second law postulates that two or more different traits are also conditioned by two or more pair of dissimilar factors and that each inhe

Class of subphylum uniramia - insecta, Class of Subphylum Uniramia - Insect...

Class of Subphylum Uniramia - Insecta Class Insecta consists of nearly a million described species. There are more species of insects as compared to all the other species of a

Define criteria for assessment of pyridoxine status, Define Criteria for As...

Define Criteria for Assessment of Pyridoxine Status? Vitamin B 6 status is most appropriately evaluated by using a combination of indicators,  namely plasma PLP concentration,

Explain the canal obstruction - endodontic retreatment, Explain the Canal O...

Explain the Canal Obstruction File work shorter than the normal apical and feel a great resistance to reach true length. a. A retained instrument o Canal calcification b.

How auxins act helping the lateral growth of the stem, How auxins act helpi...

How auxins act helping the lateral (secondary) growth of the stem? The Auxins stimulate the formation of conductive vessels, phloem and xylem, promoting the thickening of the s

What is the function of the secretions of the prostate, What is the functio...

What is the function of the secretions of the prostate, seminal vesicle and bulbourethral glands in reproduction? These secretions with sperm cells from the testicles form the

What is linkage, What is linkage? Two genes are said to be under linkag...

What is linkage? Two genes are said to be under linkage, or linked, when they reside in the same chromosome. For instance, the research of the human genome discovered that t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd