Integral membrane protein movement and distribution, Biology

Assignment Help:

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under appropriate conditions to variety a hybrid cell which is known as a heterokaryon. A mouse cells were labeled with the mouse protein-specific  antibodies to that  the  green-fluorescing  dye  fluorescein   had  been  covalently   attached, similarly  the  human  cells  were  labeled  with  the  red-fluorescing  dye  rhodamine. Upon cell fusion, the human and mouse proteins as seen under the fluorescence microscope were segregated on the two halves of the heterokaryon in figure.  After 37°C in 40 min, moreover, the mouse and human proteins had completely intermingled. Lowering the temperature to follows 15°C inhibited this procedure, denotes in which the proteins are free to diffuse laterally in the membrane and which this movement is slowed as the temperature is lowered.  It should be noted, by, that some integral membrane proteins are not free to move laterally in the membrane as they interact with the cytoskeleton inside the cell.

829_22.png

 

figure: (a) Movement and (b) distribution (as shown by freeze-fracture electron microscopy) of integral membrane proteins.

 

 


Related Discussions:- Integral membrane protein movement and distribution

Differences between mitosis and meiosis, DIFFERENCES BETWEEN MITOSIS AND...

DIFFERENCES BETWEEN MITOSIS AND MEIOSIS    EVENTS  MITOSIS  MEIOSIS  Occurrence  In all the body cells including

Advantages and disadvantages of organizational charts, Advantages and Disad...

Advantages and Disadvantages: of Organizational Charts Advantages  a)  Defining the Organizational Relationship Without a,chart, many people might view the organization as

Define influence of polyphenols on proteins, Define Influence of Polyphenol...

Define Influence of Polyphenols on Proteins? You know that tannins are considered as anti-nutritional because their presence is usually accompanied by a reduced protein digesti

How many atp molecules are made after glycolysis, How many ATP molecules ar...

How many ATP molecules are made after glycolysis? Glycolysis is a process same to glucose degradation in fermentation. It forms (final balance) two molecules of ATP for each br

Define about the pancreatic cancer, Define about the Pancreatic Cancer? ...

Define about the Pancreatic Cancer? This is a condition often associated with abdominal pain, anorexia, nausea, and vomiting and weight loss. Ealing may aggravate pain. There m

State the objectives of neuropsychological assessment, State the goals of N...

State the goals of Neuropsychological assessment Neuropsychological assessment therefore has twin goals. i) The first goal is to recognize the disrupted psychological compo

What will happen to membranes, What might happen to membranes if many -OH g...

What might happen to membranes if many -OH groups were added to the tails of phospholipids?

What are three main components of cytoskeletan, What is the cytoskeleton, a...

What is the cytoskeleton, and what are three of its main components? The cytoskeleton is a network of long protein strands located in the cytosol. Three main components are

Explain radial symmetry in classification animal kingdom, Explain Radial S...

Explain Radial Symmetry in Classification of the Animal Kingdom? All of the animals besides the sponges are considered to belong to the Eumetazoa, or the "true animals" because

Sedentary or light activity lifestyles - physical activity, How Sedentary o...

How Sedentary or light activity lifestyles affects Physical Activity? These people have occupations that do not demand much physical effort, we not required to walk long distan

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd