Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

Discuss the principle of osmolarity, These labs discuss the principle of os...

These labs discuss the principle of osmolarity, which is defined as the total number of solute particles in 1 L of solution. Is this the same thing as tonicity? Explain your answer

Five kingdom classifications, Five Kingdom Classifications Biology, as...

Five Kingdom Classifications Biology, as you know, is the study of life, living things, and their relationship to one another and to their environment. This branch of Science

Pollution - environmental pollution, Pollution - Environmental Pollution ...

Pollution - Environmental Pollution Pollution refers to any undesirable change in the physical, chemical or biological characteristics of our environment, i.e. air, water and

What organisms make glycogen, What organisms make starch? What is it used f...

What organisms make starch? What is it used for? What organisms make glycogen? What is it used for?

Which bone forms the non-moving muscle, Which bone forms the non-moving mus...

Which bone forms the non-moving muscle attachment in (a) the hip joint, (b) the shoulder joint, (c) the ankle joint?    (a) The pelvic girdle gives the non

Define descending type of paper chromatography, Define Descending type of p...

Define Descending type of paper chromatography? In descending chromatography, the movement or flow of mobile phase is in downward direction. In this technique the solvent is ke

What is nadp and nadph, What is NADP and NADPH? NADP is the abbreviatio...

What is NADP and NADPH? NADP is the abbreviation of the nicotinamide adenine dinucleotide phosphate cation, a hydrogen acceptor. NADPH is made when NADP binds to one hydrogen a

Explain rabies, Rabies  Rabies is highly prevalent in Africa, India, As...

Rabies  Rabies is highly prevalent in Africa, India, Asia and parts of Latin America, but the risk to travelers is low. Pre-exposure immunizationagainst rabies is recommended f

Explain reversion flavor, Reversion flavor:  The rapid oxidation of br...

Reversion flavor:  The rapid oxidation of branched furan fatty acids on exposure to light, leads to the production of an intensive aromatic substance, which along with diacety

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd