Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

Explain the importance of biochemical tests, Explain the Importance of Bioc...

Explain the Importance of Biochemical Tests? Specific series of biochemical tests have been developed for fast identification of microorganisms in laboratories. These biochemic

Human respiratory system - bronchioles, BRONCHUS - In thorax trachea is...

BRONCHUS - In thorax trachea is devided in to 2 bronchi that enter into lungs of its own side. Rings present in it. BRONCHIOLES - These are branches of bronchus.

The principle of dna cloning, Assume an experimental target that is to make...

Assume an experimental target that is to make vast amounts of a particular DNA fragment in pure form from a combination of DNA fragments.  Whereas the DNA fragments can be introduc

What is meant by the arch reflex, Q. What is meant by the arch reflex? ...

Q. What is meant by the arch reflex? In some situations the movement of the skeletal striated muscles does not depend upon commands of the superior motor neurons that it is not

Explain the objectives of congenital heart disease, Explain the Objectives ...

Explain the Objectives of Congenital Heart Disease ? After reading this unit, you should be able to: 1 Comprehenced the epidemiologic significance of congenital heart disease (

Vitamins requirements for ulcerative colitis, Q. Vitamins requirements for ...

Q. Vitamins requirements for ulcerative colitis? Vitamins: Commercial multivitamin preparation should be administered orally especially the ones needed for the healing process

Function of noradrenaline in consciousness, Q. Function of Noradrenaline in...

Q. Function of Noradrenaline in consciousness? Increased level of noradrenalin is implicated in wakefulness. Locus coeruleus noradrenergic neurons decrease their rate of firing

Explain hepaticae, Hepaticae (Liverworts) The gametophyte is thalloid b...

Hepaticae (Liverworts) The gametophyte is thalloid body or simple stem and leaves, with aquatic or semi-terrestrial habit. Rhizoids are multiceillular. Some examples : Mar

Endocrine system, Endocrine System The nervous system brings about in...

Endocrine System The nervous system brings about integration and co-ordination of several activities of the animal. The afferent stimuli from several sense organs are brought

Body fluids, 55yrs old woman had burns and has lost 6% body fluid.She weigh...

55yrs old woman had burns and has lost 6% body fluid.She weighs 50Kg.How much fluid does she need to replace the lost fluid.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd