Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

Disorder of platelets - purpura, Disorder of Platelets - Purpura Purpu...

Disorder of Platelets - Purpura Purpuras  are bleeding disorders characterised by petechiae  and ecchymosis which may be due to deficiency in either,  the number or quality of

Etiological factor of malabsorption syndrome, Q. Etiological factor of mala...

Q. Etiological factor of malabsorption syndrome? The causes cited for malabsorption can be associated with a number of diseases. Many of these diseases you may not know presen

Predict the genotypes and phenotypes of the f2, In rats, the gene pigment (...

In rats, the gene pigment (P) is dominant to no pigment (p). The gene for black (B) is dominant to the gene for cream (b). If a pigment gene (P) is absent, genes B and b are inoper

Explain procedure of aortic valvuloplasty, Q. Explain procedure of Aortic V...

Q. Explain procedure of Aortic Valvuloplasty? BAV is usually performed by the retrograde transarterial approach. Often another catheter is placed in the LV through transseptal

Vitamins, Which vitamin is useful for the clotting of blood?

Which vitamin is useful for the clotting of blood?

Class bivalvia, Class Bivalvia Body in a bilohed mantle enclosed in a...

Class Bivalvia Body in a bilohed mantle enclosed in a two-valved shell; head reduced; mouth with labial palps but no radula; foot wedge-shaped; plate-like gills; sexes separa

Difference between hazard and disaster, 1.      Hazard Is An Extreme Event ...

1.      Hazard Is An Extreme Event Whereas Disaster Is Its Consequence. 2.      A hazard can occur without human interference but it may become a disaster on account of careless

Determine causes of iron deficiency anaemia, Determine Causes of Iron Defic...

Determine Causes of Iron Deficiency Anaemia? Dietary Inadequacy Poor bioavailability of iron Presence of absorption interfering substances in diet Poverty and

Virus, #question.bacteria and virus are meet so what happen.

#question.bacteria and virus are meet so what happen.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd