Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

Sulphur - mineral elements, SULPHUR The major sources of sulphur are cr...

SULPHUR The major sources of sulphur are crucifers and animal proteins. Proteins present in pulses have little sulphur. Therefore, other vegetable proteins or crucifers must

Synthesis of starch, Thus animals store surplus carbohydrate as glycogen; p...

Thus animals store surplus carbohydrate as glycogen; plants do so in form of starch. Starch is producing in the stroma of chloroplasts and stored there as starch grains. The Starch

How arab influence on the development of anatomy, Please on 3 separate para...

Please on 3 separate paragraph a. Examine the contributions of select scientists from the Greek and Roman period. b. Explore the Arab influence on the development of anatomy

Illustrate thallium scintigraphy, Q. Illustrate Thallium Scintigraphy? ...

Q. Illustrate Thallium Scintigraphy? It is often done with SPECT (single photon emission computed tomography) which further increases the sensitivity. However, a stress test w

Pattern genetics, Ask questiRed-green color blindness is an X-linked recess...

Ask questiRed-green color blindness is an X-linked recessive disorder. If Allison is heterozygous (a carrier), and her husband, Michael, is NOT colorblind. What is the chance that

Cell biology, is the study of internal structure of cell included in cell b...

is the study of internal structure of cell included in cell biology or anatomy?

Demonstrate the cell membrane, While working in the lab, you isolate a cell...

While working in the lab, you isolate a cell from a mouse and a cell from a human and fuse them together to form a live, hybrid cell. You then use an antibody that recognizes all m

Theory of embryology - pre-formation theory, PR E FORMATION THEORY - ...

PR E FORMATION THEORY - Proposed by Marcello Malpighi. Studied chick egg and proposed his work in "De ova-incubato". According this different part of embryo previousl

Differential reinforcement of low response rate, Differential reinforcement...

Differential reinforcement of low response rate (DRL) This is used to encourage low rates of responding. Example: "If you ask me for a potato chip no more than once every 10 mi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd