Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

What is primary growth in shoot, What is Primary Growth in Shoot? The ...

What is Primary Growth in Shoot? The growth in height of a plant stem results from the division of cells at the apex, or tip of the stem, called the shoot tip. Here, a group o

Alkaline slant - carbohydrate utilization pattern test, Alkaline slant - Ob...

Alkaline slant - Observation for Carbohydrate Utilization Pattern Test Alkaline slant (red) and acid butt (yellow) with or without gas production - This indicates fermentation

Explain the process of growth factors, Explain the process by which growth ...

Explain the process by which growth factors promote angiogenesis. Add citation or links.

Discuss about impermeable membrane, An impermeable membrane separates one l...

An impermeable membrane separates one liter of a 0.01 M glucose solution in water in the left compartment from one liter of a 0.1 M glucose solution in water in the right compartme

What is the main external morphological feature, What is the main external ...

What is the main external morphological feature that differentiates platyhelminthes from other worms (nematodes)? Platyhelminthes are also called as flatworms because they are

What are the biological functions of the polysaccharides, Q. What are the m...

Q. What are the major biological functions of the polysaccharides? Polysaccharides have a structural function and an energy storage function. Polysaccharides incorporated by li

What is the vector of chagas disease, Q. What is the vector of Chagas' dise...

Q. What is the vector of Chagas' disease? How is the disease transmitted? The vector of the Chagas' disease is its intermediate host, a triatomine bug. The key species is Triat

Other complications in prosthetic valves, Other Complications :  Bioprosth...

Other Complications :  Bioprosthetic valves have a tendency for degeneration, calcification or cusp perforation. Current models have overcome many of these problems. Calcification

What are polysaccharides, What are Polysaccharides? Polymers of simple ...

What are Polysaccharides? Polymers of simple sugars are known as Polysaccharides. Several polysaccharides, unlike sugars, are insoluble in water. Dietary fibre includes polysac

Determine the term - language abilities, Determine the term -  Language Ab...

Determine the term -  Language Abilities The study of aphasia and acquired language disorders was one of the driving forces in the growth of neuropsychology in this century. Th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd