Hypothermia-open heart surgery, Biology

Assignment Help:

Hypothermia :  Hypothermia reduces the metabolic requirements of the body thereby reducing oxygen consumption. It also preserves high-energy phosphate stores of the body. At normal temperature, if there is circulatory arrest for three minutes, brain suffers hypoxic damage. At 30°C, this period extends up to 10 minutes. If the temperature is brought down to l8°C, this period extends up to 45 minutes. .In 1953, John Lewis used surface hypothermia up to 280C and by inflow occlusion method closed atrial septa1 defect while the heart was arrested for 5.5 minutes. Japanese surgeons started surface cooling followed by short period of core cooling to achieve deep hypothermia (l8°C) to have circulatory arrest to correct complicated intra cardiac lesions in babies. Surface cooling being a cumbersome procedure, these days both cooling and re warming are done on tile pump. In this technique of deep hypothermia and circulatory arrest (DHCA), it is safe if the period of arrest is 30 minutes or less. Between 30 minutes and 45 minutes, it is relatively safe. Above one hour, brain damage is likely to occur. In adults, the same technique is used for aortic arch aneurysms and pulmonary thrombo-endarterectomy. At the time of circulatory arrest, retrograde cerebral perfusion with cold perfusate through superior vena cava (cerebroplegia) is practised.

 


Related Discussions:- Hypothermia-open heart surgery

Explain about the bifidogenic effect, Explain about the Bifidogenic Effect?...

Explain about the Bifidogenic Effect? Fructans selectively stimulate the growth of Bifidobacteria and Lactobacilli, while decreasing concentrations of E.coli, Clostridia and ba

Bovine ephemeral fever, B o v i ne ephemeral fever Ephemeral fever ...

B o v i ne ephemeral fever Ephemeral fever is commonly known as 'three-day sickness'. It affects mainly cattle and occasionally sheep in India. Causative agent is a mosquit

Formation of an h+ gradient, All of the electron carrier in the electron tr...

All of the electron carrier in the electron transport chain interact according to their redox potentials.  Every time whereas an electron transfers occurs, the accepting carrier ha

Rituals , Rituals: The social life of  the earliest human groups or tri...

Rituals: The social life of  the earliest human groups or tribes revolved around food gathering. To begin with, they must have collected anything they could eat-seeds,  nuts, f

Spirochetosis (tick fever), S p ir ochetosis (tick fever) This is di...

S p ir ochetosis (tick fever) This is disease of young birds under poor management mostly reared as backyard poultry caused by a spiral bacterium, Borrelia anserina and tr

What is phylum annelida - segmented worms, What is Phylum Annelida - Segmen...

What is Phylum Annelida - Segmented Worms? Members of this Phylum are commonly known as the segmented worms. The body of a segmented worm is made of many individual ring-like s

Explain the skin fold method to measure body fats, Explain the Skin fold me...

Explain the Skin fold method to measure body fats? The skin fold method utilizes predication of body fat from sum of three or four skin folds (at biceps, triceps, sub scapular,

Define post-surgical nutrition support for chd patient, Define Post-surgica...

Define Post-surgical Nutrition Support for CHD Patient? Nutrition support should be started as soon as possible. If oral not possible, enteral nutrition support should be pr

Describe about the mitochondrial membranes, Describe about the mitochondria...

Describe about the mitochondrial membranes The composition of the two mitochondrial membranes is entirely different. The outer membrane is rich in lipids and contains nearly 50

Explain about vitamin C, Vitamin C (Ascorbic acid) Vitamin C, ascorbic ...

Vitamin C (Ascorbic acid) Vitamin C, ascorbic acid is also called anti-scorbutic vitamin. Ascorbic acid occurs as white crystals or white crystalline powder without odour and o

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd