How tert-butylamine is prepared, Chemistry

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Tert-butylamine

Tert-butylamine cannot be prepared by the Gabriel synthesis because it would require that the nitrogen of phthalimide be alkylated with tert-butyl bromide in an SN2 reaction.  Tertiary alkyl halides generally do not undergo SN2 reactions but, under basic conditions, undergo E2 reactions instead.

 

 


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