How aggregation occur in sickle-cell anemia, Biology

Assignment Help:

How does aggregation occur in sickle-cell anemia? Place the steps in the correct order from no aggregation to sickle red blood cell. Note that deoxyhemoglobin is generally in the T state; oxyhemoglobin is in the R state.


Additional T state HbS interact with the growing aggregation to form an insoluble fiber.

Val interacts with the "pocket" of a beta chain on another HbS.

R state Hb shifts to T state Hb

O2 decreases due to vigorous exercise or high altitude.


Related Discussions:- How aggregation occur in sickle-cell anemia

Second stage of invagination, Second Stage of Invagination The 2 nd s...

Second Stage of Invagination The 2 nd stage of invagination starts with release of secondary mesenchyme from the tip of archenteron into the blastocoel. The cells of secondar

Behaviour modifications for weight reduction plan, Define Behaviour and Lif...

Define Behaviour and Life Style Modifications for Weight Reduction Plan? Behaviour and life style modifications are an integral part of the weight reduction plan. They are base

Why is pattern baldness more common in men than in women, Why is pattern ba...

Why is pattern baldness more common in men than in women? Pattern baldness is handled by the allele B. Testosterone interacts with the heterozygous genotype (BB′) to make baldn

Determine the importance of calcium in soils, Determine the importance of C...

Determine the importance of Calcium in soils Calcium in soils is usually abundant except in acid soils, which occur in humid areas due to excessive leaching. Deficiency of calc

What are mycotoxins, Q. What are mycotoxins? How are these produced and w...

Q. What are mycotoxins? How are these produced and where are these found? Are these naturally-occurring or produced? What is their significance? First what are mycotoxins?

I dont know, What are two specific organs that work together to preform a f...

What are two specific organs that work together to preform a function??

Explain the multiple organ dysfunction syndrome (mods), Explain the Multipl...

Explain the Multiple Organ Dysfunction Syndrome (MODS) Failure of essential organs is the most severe complication of sepsis and may result in death. The treatment of systemic

Organization chart, ORGANIZATION CHART: Organization chart is one of  ...

ORGANIZATION CHART: Organization chart is one of  the visual which helps any visitor to get an understanding of an organization at a glance.  Meaning of Organization Chart

Describe the biological parameters of living organisms, Describe the Biolog...

Describe the Biological parameters of living organisms Biological parameters which include living organisms constitute an important component of soil.  Even though organisms fo

Indications for surgery-mitral valve disease, Indications for Surgery :  T...

Indications for Surgery :  The normal mitral valve area is 4-5 cm 2 . Usually symptoms appear when the valve area has become less than 2.5 cm2. Symptoms are present at rest when t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd