Feline panleukopenia
It is arguably the most important of all feline viral diseases and all members of the family Felidae are susceptible. This disease is commonly found in kittens and in most species of felines caused by a virus of Parvoviridae family. Its symptoms include acute leucopenia when the white blood cell count may be fewer than 100/mm³. The disease could be quite severe and highly fatal. High fever, profuse persistent diarrhoea and dehydration are some clinical features. Confirmatory test includes, direct hemagglutination of swine or rhesus monkey RBCs by virus present in suitably prepared fecal samples, virus isolation in cell culture, antigen capture enzyme immunoassays or immunofluroscence for the detection of antigen in tissues and PCR assay for the detection of viral DNA in tissues could be used for diagnoses. Vaccination is universally practiced with both attenuated and inactivated virus. Due to interference by the maternal antibody, vaccine failures frequently occurs.