Explain rifabutin, Biology

Assignment Help:

Explain Rifabutin

Two alternative regimens are based on the fact that rifabutin appears to be as effective as rifampin against TB, and has less effect on protease inhibitor levels. The first substitutes low-dose rifabutin (150 mg once/day or 300 mg 3x/week) for rifampin in the standard regimen (i.e., isoniazid, rifabutin, pyrazinamide and ethambutol) and uses higher than usual doses of indinavir (Crixivan) or nelfinavir (Viracept), or standard doses of amprenavir (Agenerase) or fos amprenavir (Lexiva)  as the protease inhibitor.

The second decreases the rifabutin dose further to 150 mg every other day or 3 times weekly and gives it with standard doses of atazanavir  (Reyataz), ritonavir/lopinavir (Kaletra) or ritonavir alone or combined with other protease inhibitors. Saquinavir (Fortovase, Invirase) alone should not be used. If the HAART regimen contains nevirapine, the usual dose of rifabutin should be used. Higher rifabutin doses (450-600 mg daily) are needed if the HAART regimen contains efavirenz.

 


Related Discussions:- Explain rifabutin

Full form of hiv and aids, HIV (Human Immuno Deficiency Virus) Infection a...

HIV (Human Immuno Deficiency Virus) Infection and AIDS (Acquired Immune Deficiency Syndrome)

What is the reason of post endodontic disease, What is the reason of post e...

What is the reason of post endodontic disease ? Either there is persistent or reintroduce intracanal microorganisms.. that means if I do improper instrumentation, improper clea

Categorisation of neuropsychological assessment, Categorisation of Neuropsy...

Categorisation of Neuropsychological Assessment One can divide neuropsychological assessment into two areas: i) Comprehensive and ii) Specialised assessment. Comprehen

smog - london smog and photochemical smog, The word 'smog' consists of two...

The word 'smog' consists of two words 'smoke' and 'fog'. This name was given because Fog in the atmosphere Condense on the carbon particles of smoke to form smog. There are two typ

Chemicals of life, give two examples of chemical reactions which are cataly...

give two examples of chemical reactions which are catalysed by enzymes in the course of brewing

Obelia, why is it consideredto have an intermideate grade oforganisation

why is it consideredto have an intermideate grade oforganisation

Can you define factor viii, Q. What is factor VIII? What is the genetic dis...

Q. What is factor VIII? What is the genetic disease in which this factor is absent? Factor VIII has the function of activating factor X that in its turn is necessary for the tr

Financing of healthcare - constraints, Financing of Healthcare - Constraint...

Financing of Healthcare - Constraints One of the major constraints to improve the healthcare delivery system in developing countries is weak public sector management. These ec

Explain procedure for capsule staining in a culture, Explain Procedure for ...

Explain Procedure for Capsule Staining in a Culture? We have learnt that Capsule staining can be undertaken either by negative staining or Anthony method. Now carry out the exe

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd