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Explain Lamivudine
It is probably the best tolerated of the NRTIs and can be taken once or twice daily. An increase in viral load during treatment with a lamivudine-containing regimen is often an indication of resistance to lamivudine. Lamivudine-resistant strains may be cross-resistant to zalcitabine and emtricitabine, and may have low-level resistance to abacavir, ddI and ddC.
Ideal Characteristics 1) Maximize gas transfer (oxygen, carbon dioxide and anaesthetic gases) 2) Minimize blood trauma 3) Good heat transfer efficiency 4) Minimize
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