Explain Fosamprenavir calcium

It is a prodrug of amprenavir, was recently approved by the FDA for use in HAART. In patients who have not lastly been treated with a protease inhibitor, fosamprenavir can be taken once daily combined with ritonavir, or twice daily with or without ritonavir. In patients who are treatment-experienced, it should be taken twice daily with ritonavir. If coadministered with ritonavir and efavirenz, the ritonavir dosage should be increased. Fosamprenavir will likely replace amprenavir, because the total number of pills taken every day is lower.