Explain Food Effects on Drug Excretion?

Food and nutrients can alter the re-absorption of drugs from the renal tubes. Urinary acidity affects drug re-absorption from the renal tubules. Hence, a change in urinary pH by food may change the amount of drug existing in the nonionic state, thus increasing or decreasing the amount of drug available for tubular reabsorption. Supplemental intakes of nutrients, which increase urinary acidity (e.g., large amounts of vitamin C intake), can decrease the excretion of salicylate drugs such as asprin. In our discussion, so Jar we focused on the effect of food or nutrients on drugs absorption, utilization, metabolism, excretion etc. Let us now move on to the effects of nutrient supplements on drugs.