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Explain Carbamoyl Phosphate Synthetase (CPSI) ?
In the first step, the mitochondria1 enzyme Carbamoyl Phosphate Synthetase 1 converts the ammonia produced by glutamate dehydrogenase into carbarnoyl phosphate.
See Figure which illustrates the entire urea cycle. The formation of carbamoyl phosphate requires 2 molecules of ATP and takes place in the matrix of mitochondria. The ammonium may come from glutamate (as learnt earlier by the action of L-glutamate dehydrogenase) or in free form (as NH,) from blood. Pi is inorganic phosphate. ATP, as usual, functions as a magnesium-ATP complex. Carbamoyl phosphate is further transferred to ornithine. Let us learn about this in the next step.
Explain Genetic Theory of ageing Rate of ageing varies between species. The difference is in the genetic changes in the species. Thus it can be said that gradual impairment of
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