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Explain Carbamoyl Phosphate Synthetase (CPSI) ?
In the first step, the mitochondria1 enzyme Carbamoyl Phosphate Synthetase 1 converts the ammonia produced by glutamate dehydrogenase into carbarnoyl phosphate.
See Figure which illustrates the entire urea cycle. The formation of carbamoyl phosphate requires 2 molecules of ATP and takes place in the matrix of mitochondria. The ammonium may come from glutamate (as learnt earlier by the action of L-glutamate dehydrogenase) or in free form (as NH,) from blood. Pi is inorganic phosphate. ATP, as usual, functions as a magnesium-ATP complex. Carbamoyl phosphate is further transferred to ornithine. Let us learn about this in the next step.
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Objectives : After studying this unit, you should be able to: 1. List the obligations of the teachers and the Head of the institution towards 2. Safe working conditions
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