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Explain Carbamoyl Phosphate Synthetase (CPSI) ?
In the first step, the mitochondria1 enzyme Carbamoyl Phosphate Synthetase 1 converts the ammonia produced by glutamate dehydrogenase into carbarnoyl phosphate.
See Figure which illustrates the entire urea cycle. The formation of carbamoyl phosphate requires 2 molecules of ATP and takes place in the matrix of mitochondria. The ammonium may come from glutamate (as learnt earlier by the action of L-glutamate dehydrogenase) or in free form (as NH,) from blood. Pi is inorganic phosphate. ATP, as usual, functions as a magnesium-ATP complex. Carbamoyl phosphate is further transferred to ornithine. Let us learn about this in the next step.
Maintain the Calcium Levels of Body– Function of Kidney Maintain the body’s calcium levels. Along with parathormone and calcitriol, kidney helps the body to absorb calcium.
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